Compositions for imaging of the gastrointestinal tract

Details Compositions for imaging of the gastrointestinal tract Compositions for imaging of the gastrointestinal tract

1996-12-19

1999-02-02

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

X-ray contrast imaging agent

424 9454, 560 37, 560 43, A61K 4904

Patent

active

058661000

ABSTRACT:
The invention relates to non-ionic triiodo aromatic compounds and compositions comprising triiodo aromatic polymers useful for X-ray imaging of gastro-intestinal tract. Disclosed compounds are acrylic acid esters of triiodobenzenes with a different degree of reticulation and their polymers/homopolymers. A method of making the polymers, method of making X-ray contrast agents using the polymers and use of the contrast agents is also disclosed.

REFERENCES:
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patent: 4584401 (1986-04-01), Sovak et al.
patent: 5536490 (1996-07-01), Klaveness et al.
Hoey, GB et al., Invest. Radiol 15(6 suppl.):s289-s295 (1980).

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