Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Patent
1990-12-21
1995-11-07
Draper, Garnette D.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
424 941, 4242041, 4241471, 4241591, 530402, 530826, 536 2372, 574 8, A61K 3843, A61K 3912, C07K 200, C07K 1700
Patent
active
054649366
ABSTRACT:
Medicaments, and methods of identifying the same, are described that are useful for treating papillomavirus diseases that have the characteristics of preventing, interfering with, or reversing the binding of the appropriate papillomavirus proteins E1 or E2 to a nucleotide sequence homologous to a nucleotide sequence present in the papillomavirus genome, or of the formation of a complex consisting of papillomavirus proteins E1 and E2, or the binding of the complex to the nucleotide sequence.
REFERENCES:
Lambert et al 1988 J Virol. 62:4009-4015.
Schiller et al 1989 J Virol 63: 1775-1782.
Sekine et al., 1988, Gene, 65:187-193.
Mohr et al., 1990, Science, 250:1694-1699.
Chiang et al., 1991, J. of Virology, 65(6):3317-3329.
Blitz et al., 1991, J. of Virology, 65(2):649-656.
Botchan Michael R.
Clark Robin
Mohr Ian J.
Sun Shaw
Carlson K. Cochrane
Cetus Oncology Corporation
Draper Garnette D.
University of California
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