Compositions for eliciting an immune response against...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C530S350000, C514S012200, C424S248100

Reexamination Certificate

active

07732580

ABSTRACT:
Provided are compositions and methods for stimulating an immune response againstMycobacterium aviumsubspeciesparatuberculosis(MAP). The compositions include a recombinant polypeptide that contains from its N-terminus to C-terminus a C-terminal fragment of MAP protein Map3527, a Map1519 protein amino acid sequence, followed by an N-terminal portion of Map3527. The method comprises administering the composition to an animal in an amount effective to stimulate an immunological response against MAP bacteria. The method is of benefit to any animal susceptible to MAP infection, but is particularly beneficial for ruminants.

REFERENCES:
patent: 7074559 (2006-07-01), Kapur et al.
patent: 2007/0042383 (2007-02-01), Kapur et al.
patent: 2007/0134274 (2007-06-01), Talaat
patent: 2006/089043 (2006-08-01), None
patent: WO-2006089043 (2006-08-01), None
patent: WO-2006089043 (2007-04-01), None
Chen,Li et al, Vaccine, 2008, vol. 26, pp. 1253-1262, Immune reponses in mice toMycobacterium aviumsubsp. paratuberculosis following vaccination with a novel 74F recombinant polyprotein.
Buergelt C.D. et al., Nested Polymerase Chain Reaction and Prenatal Detection ofMycobacterium aviumSubspecies paratuberculosis (Map) in Bovine Allantoic Fluid and Fetuses. International Journal of Applied Research in Veterinary Medicine. 2006, vol. 4, No. 3, pp. 232-238.
Dheenadhayalan V. et al. Cloning and characterization of the genes coding for antigen 85A, 85B and 85C ofMycobacterium aviumsubsp. paratuberculosis. DNA Sequence, 2002; 13(5):287-294.
Kalis C. H. et al. Use of long-term vaccination with a killed vaccine to prevent fecal shedding ofMycobacterium aviumsubsp paratuberculosis in dairy herds. Am J Vet Res 2001;62(2):270-4.
Koets A.P. et al., Genetic variation of susceptibility toMycobacterium aviumsubsp. paratuberculosis infection in dairy cattle. J Dairy Sci 2000;83(11):2702-8.
Kormendy B. Paratuberculosis vaccine in a large dairy herd. Acta Vet Hung 1992;40(3):171-84.
Li L. et al., The complete genome sequence ofMycobacterium aviumsubspecies paratuberculosis. Proceedings National Academy Sciences (USA). Aug. 30, 2005, vol. 102, No. 35, pp. 12344-12349 and GenBank Accession No: AE016958.
Mullerad J. et al. The immunogenicity ofMycobacterium paratuberculosis85B antigen. Med. Microbiol. Immunol. 2002; 190:179-187.
PCT/US/08/79425 International Search Report. Jan. 14, 2009. 3 pp.
Sechi L.A., et al. Immunogenicity and cytoadherence of recombinant heparin binding haemagglutinin (HBHA) ofMycobacterium aviumsubsp. paratuberculosis: Functional promiscuity or a role in virulence? Vaccine 2006;24(3):236-243.
Shin S.J. et al. Comparative antibody response of five recombinant antigens in related to bacterial shedding levels and development of serological diagnosis based on 35 kDa antigen forMycobacterium aviumsubsp. paratuberculosis, J. Vet. Sci. 2004; 5(2), 111-117.
Shin S.J. et al. In vitro cellular immune responses to recombinant antigens ofMycobacterium aviumsubsp. paratuberculosis. Infect Immun 2005;73(8):5074-85.
Uzonna J.E. et al. Efficacy of commercial and field-strainMycobacterium paratuberculosisvaccinations with recombinant IL-12 in a bovine experimental infection model. Vaccine 2003, vol. 21, pp. 3101-3109.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compositions for eliciting an immune response against... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions for eliciting an immune response against..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions for eliciting an immune response against... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4227468

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.