Compositions for controlling bacterial colonization

Details Compositions for controlling bacterial colonization Compositions for controlling bacterial colonization

1999-02-12

2000-12-12

Weddington, Kevin E.

Drug, bio-affecting and body treating compositions

Dentifrices

424 50, 514 2, 514 23, A61K 716, A61K 728, A61K 3800, A61K 3170

Patent

active

061594474

ABSTRACT:
A composition for controlling bacterial growth/colonization is provided. The composition comprises a selected enzyme, a selected anchor molecule coupled to the enzyme to form an enzyme-anchor complex, with the anchor being capable of attaching to a substrate proximal to a bacterial colony. The attachment to the substrate permits prolonged retention time of the enzyme-anchor complex where the bacterial colony is present to increase the effectiveness of the complex. The invention is also for a method of controlling colonization of bacterial plaque in the oral cavity, as well as a method of forming a composition for controlling the proliferation of bacterial colonies in the oral cavity.

REFERENCES:
patent: 5202113 (1993-04-01), London
patent: 5362480 (1994-11-01), Au et al.
patent: 5871714 (1999-02-01), Budny

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