Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1987-09-02
1989-10-31
Lander, Ferris H.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424438, A61K 916
Patent
active
048776211
ABSTRACT:
A composition for coating a biologically active substance, which is stable in a medium with a pH greater than or equal to 5 and which enables the active substance to be released in a medium with a pH less than or equal to 3.5, consisting of a basic amino copolymer (preferably vinyl-pyridine/styrene copolymer) and a hydrophobic substance with a melting point greater than 60.degree. C. (preferably stearic acid), the hydrophobic substance content being between 50 and 90% of the total mass of the coating, and granules comprising a nucleous containing the biologically active substance, coated with this composition.
REFERENCES:
patent: T100404 (1981-03-01), Wu
patent: 4196187 (1980-04-01), Dannelly et al.
patent: 4675175 (1987-06-01), Autant et al.
Ardaillon Pierre
Autant Pierre
Bourrain Paul
Cartillier Andre
Green Anthony J.
Lander Ferris H.
Rhone-Poulenc Sante
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