Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1997-09-23
1999-11-02
Fonda, Kathleen K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
536 41, 536 172, 536 179, 514 61, 514 62, A61K 3170, C07H 1500
Patent
active
059770791
ABSTRACT:
Antibody-mediated xenograft rejection is attenuated by (1) removing preformed antibodies to various identified carbohydrate xenoantigens from the recipient's circulation prior to transplantation by extracorporeal perfusion of the recipient's blood over a biocompatible solid support to which the xenoantigens are bound and/or (2) parenterally administering a xenoantibody-inhibiting amount of an identified xenoantigen to the recipient shortly before graft revascularization and thereafter.
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Cooper David K.C.
Good A. Heather
Malcolm Andrew J.
Alberta Research Council Edmonton
Fonda Kathleen K.
Integris Baptist Medical Center, Inc.
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