Compositions corresponding to a proton-coupled peptide transport

Details Compositions corresponding to a proton-coupled peptide transport Compositions corresponding to a proton-coupled peptide transport

1995-12-21

1998-12-15

Walsh, Stephen

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

536 235, 530350, 435 72, 435325, C12N 1512, C07K 1447, C07K 14705, C12P 2102

Patent

active

058495258

ABSTRACT:
The present invention relates to nucleic acid and amino acid sequences corresponding to a proton-coupled peptide transporter and methods of making and using such transporter.

REFERENCES:
patent: 5500346 (1996-03-01), Bright et al.
Yusei Miyamoto et al., The Journal of Biological Chemistry, pp. 4742-4745, vol. 266, No. 8, Mar. 15, 1991, "Functional Expression of the Intestinal Peptide-Proton Co-transporter in Xenopus laevis Oocytes".
Yi-Fang Tsay et al., Cell Press, pp. 705-713, vol. 72, Mar. 12, 1993, "The Herbicide Sensitivity Gene CHL1 of Arabidopsis Encodes a Nitrate-Inducible Nitrate Transporter".
Werner Kramer, et al., Feb. 1992, "Intestinal absorption of .beta.-lactam antibodies and oligopeptides", pp. 923-930, Hoechst Aktiengesellschaft, Frankfurt am Main, Federal Republic of Germany.
Hannelore Daniel et al., J. Clin. Invest., vol. 92, Nov. 1993, pp. 2215-2223, "Transport of .beta.-Lactam Antibiotics in Kidney Brush Border Membrane".
Bai JP et al., Journal of Pharmaceutical Sciences 81(2): 113-6, 1992 Feb., Abstract, "Utilization of peptide carrier system to improve intestinal absorption: targeting prolidase as a prodrug-converting enzyme".
Nature 360:467-461 (03 Dec. 1992), Kamat et al Primary structure and functional characteriaztion of a high-affinity glutaunate transporter.
J. Biol. Chem. 267:649-652, (05 Jan. 1992) Yamauchi et al cloning of a Na-and Cl-dependant betaine transporter that is requlated by hypertonicity.
P.N.A.S. 89:1-5, (Jan. 1992) Tate et al Expression cloning of a Nat-independant neutral amnio acid transporter from vat kidney.
Nature 330:379-381, (26 Nov. 1987) Heliger et al. Expression clousing and cDNA sequency of the Natl glucose co-transporter.
J. Brok Clem, 267:6297-63.1, (25 Mar. 1992) Kuon et al cloning of the cDNA for a Nat/myo-inositol transporter, a hypertonicity stress protein.

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