Compositions corresponding to a high-affinity glutamate transpor

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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530395, 536 231, 536 235, C07K 1447, C07K 14705, C12N 1512

Patent

active

057392846

ABSTRACT:
The present invention features an excitatory amino acid carrier protein which has high affinity for glutamate and is associated with neuronal glutamate transport, and methods of making and using the protein.

REFERENCES:
D. Nicholls et al. Trends in Phamacol. Sci. 11:462-468 (1990).
R.D. Blakely et al. Proc. Natl. Acad. Sci 85:9846-9850 (Dec. 1988).
M.A. Hediger et al. Nature 330:379-381 (Nov. 1987).
N.C. Danbolt et al. Neuroscience 51(2) 295-310 (1992).
N.C. Danbolt et al. Biochemistry 29:6734-6740 (1990).
B.I. Kamner et al. FEBS Letts. 94(2) 245-248 (1978).

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