Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1998-06-17
2000-08-01
Stucker, Jeffrey
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
424 941, 514 2, 514 21, 530356, 530380, 530381, 530382, 435 13, 435188, A61K 3800
Patent
active
060963093
ABSTRACT:
The present invention relates to thrombin-containing hemostatic compositions, their preparation and use. In particular, it relates to hemostatic compositions comprising stabilized thrombin and microfibrillar collagen in an aqueous medium. In a preferred embodiment of the present invention, the compositions are used in a kit comprising two different components, one of which is autologous patient's plasma as the source of fibrinogen, and the other of which is the thrombin-containing composition which also contains microfibrillar collagen having an average diameter of about 3-30 nanometers.
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DeLustro Frank A.
Prior Jeffrey J.
Sierra David H.
Wallace Donald G.
Axford Laurie A.
Cohesion Technologies, Inc.
Stucker Jeffrey
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