Compositions containing platinum

Details Compositions containing platinum Compositions containing platinum

1978-10-17

1980-09-30

Sneed, Helen M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07F 1500

Patent

active

042255295

ABSTRACT:
A cis co-ordination compound of platinum having the structure ##STR1## in which X and Y are the same or different ligands selected from halide, sulphate, phosphate, nitrate, carboxylate, carboxylate substituted with halogen and water and A and B are the same or different straight-chain alkyl amines containing at least 3 carbon atoms in the alkyl chain co-ordinated to the Pt through their N atoms, such that the platinum is present as Pt.sup.2+.

REFERENCES:
patent: 3892790 (1975-07-01), Tobe et al.
patent: 3904663 (1975-09-01), Tobe et al.
patent: 4115418 (1978-09-01), Gale et al.
patent: 4140707 (1979-02-01), Cleare et al.
Cleare et al., Platinum Metal Rev., 17, pp. 4, 8, 11, (1973).
Leh et al., J. Pharmaceutical Sciences, 60, (3), pp. 315-320, (1976).
Cleare et al., Bioinorganic Chemistry, 2, pp. 191, 196, 199, (1973).
Meischen et al., J. Natl. Cancer Inst., 57, (4), pp. 841-845, (1976).
Tobe et al., J. of Clinical Hematology and Oncology, vol. 7, No. 1, pp. 116, 127, 131, (1971).

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