Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1978-10-18
1980-05-20
Sneed, Helen M. S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424287, C07F 1500
Patent
active
042039126
ABSTRACT:
A cis co-ordination compound of platinum having the structure ##STR1## in which X and Y are the same or different ligands selected from sulphate, phosphate, nitrate, tartronate, benzylmalonate, cyclobutane-1, 1-dicarboxylate, phthalate, oxalate, tartrate, pyruvate, gluconate, succinato, glutarato, adipato, pimelato and malato and water and A and B are the same or different alicyclic amines selected from cyclopentamine and cyclohexylamine co-ordinated to the Pt through their N atoms, such that the platinum is present as Pt.sup.2+.
REFERENCES:
patent: 3892790 (1975-07-01), Tobe et al.
patent: 3904663 (1975-09-01), Tobe et al.
patent: 4115418 (1978-09-01), Gale et al.
Connors et al., Platinum Coordination Complexes in Cancer Chemotherapy, Springer-Verlag, N.Y., pp. 13-20, 135 (1974).
Cleare et al., Platinum Metal Rev., 17, 4, 8, 11 (1973).
Hydes Paul C.
Malerbi Bernard W.
Johnson Matthey & Co., Limited
Sneed Helen M. S.
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