Compositions containing immunogenic molecules and granulocyte-ma

Details Compositions containing immunogenic molecules and granulocyte-ma Compositions containing immunogenic molecules and granulocyte-ma

1996-02-09

2000-08-01

Navarro, Albert

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

4241851, 4242771, 435975, 530300, 530328, 530350, A61K 3900, A61K 3938, A61K 3800, C07K 100

Patent

active

060963131

ABSTRACT:
Granulocyte-macrophage colony stimulating factor ("GM-CSF") has been found to act as an adjuvant when administered to subjects. Compositions of GM-CSF and immunogenic compositions are presented, as is the use of GM-CSF alone and in these compositions.

REFERENCES:
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patent: 5976546 (1999-11-01), Laus et al.
Dranoff et al., "Vaccination With Irradiated Tumor Cells-Engineered to Secrete Murine Granulocyte-Macrophage Colony Stimulating Factor Stimulates Potent, Specific, And Long Lasting Anti-Tumor Immunity", Proc. Natl. Acad. Sci. USA 90: -3539-3543 (Apr. 1993).
Cellular & Molecular Immunology, Abbas et al Editor, W. B. Saunder Comp. Philadelphia, 1991 pp. 245-248.
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Perkins et al (American Journal of Hematology Aug. 1993 43(4) pp. 279-285).
Lazar et al (Molecular & Cellular Biology vol. 8 No. 3, Mar. 1988 pp. 1247-1252).
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