Compositions containing forskolin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3135

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active

053711041

ABSTRACT:
The invention relates to a process for the solubilzation of forskolin, to the pharmaceutical compositions based on such solubilized forskolin and to the use of these in the treatment of various diseases and disorders and maladies in mammals, including human. Forskolin is 7-beta-acetoxy-8,13-epoxy-1-alpha,6-beta,9-alpha-trihydroxylabd-14-en-11-o ne.

REFERENCES:
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patent: 4564626 (1986-01-01), Kreutner et al.
patent: 4588724 (1986-05-01), Greenway et al.
patent: 4724238 (1988-02-01), Dohadwalla et al.
patent: 4782082 (1988-11-01), Kreutner et al.
patent: 4871764 (1989-10-01), Shutske
Huang et al., "Inhibition of Forskolin-Activated Adenylate Cyclase by Ethanol and Other Solvents," J. Cyclic Nucleotide Res., 8(6):385-394 (1982).
Chemical Abstracts: vol. 110 (25) 225312(t) (1989).
Chemical Abstracts: vol. 111(14) 120890(x) (1990).

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