Compositions containing fixed combinations

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514182, 514843, 514899, A61K 3156

Patent

active

052082253

ABSTRACT:
Continuous administration of compositions containing a fixed quantity of synthetic estrogen in combination with a synthetic progestogenic agent are useful to relieve menopausal symptoms, to prevent osteoporosis and for other hormone-replacement treatments. Also described is an improved manufacturing process for such compositions especially for low tablet dosage forms.

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patent: 4425339 (1984-01-01), Pitchford
patent: 4826831 (1989-05-01), Plunkett et al.
patent: 5108995 (1992-04-01), Casper
Abstract from "Abstracts of Current, Clinical and Basic Investigation" 35th Annual Clinical Meeting, Apr. 27-30, Las Vegas, Nev.
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The Lancet, Oct. 12, 1985, by C. Christiansen, et al. p. 800, column 2.
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Aust. N.Z.J. Obstet Gynaec., 1983, pp. 43-47.
Collection of chapters from "Hormone Therapy of the Menopause and Aging".
The Merck Index; 10th Ed. (1983); pp. 542, 960.

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