Compositions containing difluprednate

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514912, A61K 3156

Patent

active

061143197

ABSTRACT:
The present invention relates to a liquid composition comprising difluprednate, oil, water and an emulsifier. The composition of the present invention has superior antiinflammatory action and antiallergic action. The composition of the present invention shows superior transfer to a lesion and uniform drug distribution upon administration, as compared to conventional preparations containing difluprednate, so that it shows sufficient efficacy in a smaller dose. The inventive composition is associated with extremely less uncomfortable feeling and foreign sensation upon administration, as compared to conventional preparations containing difluprednate, and it can be administered easily to local sites of eye, nose, ear and the like.

REFERENCES:
patent: 3780177 (1973-12-01), Ercoli et al.
patent: 4427670 (1984-01-01), Ofuchi et al.
patent: 5556848 (1996-09-01), Kimura et al.

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