Compositions containing corticosteroids or analogues thereof and

Details Compositions containing corticosteroids or analogues thereof and Compositions containing corticosteroids or analogues thereof and

1993-04-20

1995-02-07

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514178, 514182, 552634, 552636, 424 9371, A61K 31565

Patent

active

053875834

ABSTRACT:
3.beta.,17.beta.-androstenediol (".beta.AED") and 3.beta.,7.beta.,17.beta.-androstenetriol (".beta.AET") may be used to counteract the antiproliferative and immunosuppressive effects of hydrocortisone and other corticosteroids (i.e., to act as buffers to counteract the lymphosuppressive response to such steroids). .beta.AED and .beta.AET are steroids which mediate immune response to provide the body protection against immune down-regulation. A method for testing analogues of .beta.AED and .beta.AET to compare the effectiveness of such analogues as buffers of certain effects of hydrocortisone and other corticosteroids, including immune response and proliferative effects is described. Cytokines, including most particularly IL-3, are produced by addition of .beta.AET and .beta.AED and their analogues to the growth media of cell cultures of lymphatic cells.

Affiliated with

Also associated with

Rating

Compositions containing corticosteroids or analogues thereof and does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions containing corticosteroids or analogues thereof and, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions containing corticosteroids or analogues thereof and will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1110436