Compositions containing 5.alpha.-dihydro-19-norethisterone and d

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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552649, A61K 3156, C07J 100

Patent

active

049786580

ABSTRACT:
A composition for in vivo inhibition of aromatase in a mammal, which comprises an in vivo inhibitory amount of a compound having the following general formula: ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-4 acyl, in combination with as pharmaceutically acceptable carrier or diluent thereof.

REFERENCES:
Yoshio Osawa et al.; Irreversible Inhibitors of Oestrogen . . . ; Biochemical Society Transactions, vol. 11, pp. 656-659 (1983).

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