Compositions containing 5-.alpha.-dihydro-19-norethisterone and

Details Compositions containing 5-.alpha.-dihydro-19-norethisterone and Compositions containing 5-.alpha.-dihydro-19-norethisterone and

1989-03-09

1991-03-05

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

435184, 552592, A61K 3156, C12N 999

Patent

active

049978276

ABSTRACT:
A composition for in vivo inhibition of aromatase in a mammal, which comprises an in vivo inhibitory amount of a compound having the following general formula: ##STR1## wherein R.sub.1 is hydrogen or C.sub.1-20 acyl, in combination with a pharmaceutically acceptable carrier or diluent thereof.

REFERENCES:
patent: 3937827 (1976-02-01), Babcock et al.
patent: 4829059 (1989-03-01), Osawa
Bowers et al., Jacs, 80, 1958, pp. 6115-6118.
Morrison and Boyd, Organic Chemistry (Boston, Allyn and Bacon), 1979, pp. 602-603.

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