Compositions containing 1.alpha.-hydroxycholecalciferol for topi

Details Compositions containing 1.alpha.-hydroxycholecalciferol for topi Compositions containing 1.alpha.-hydroxycholecalciferol for topi

1988-09-08

1989-11-07

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514167, 514861, 514863, A61K 3159, A61K 3170

Patent

active

RE0331074

ABSTRACT:
Cosmetic and dermatological compositions containing 1.alpha.-hydroxycholeciferol and a suitable carrier useful in topical treatment of skin disorders and methods employing same are disclosed. Compositions containing 1.alpha.,25-dihydroxycholecalciferol and a suitable carrier and methods employing same are also disclosed for dermatological and cosmetic uses. Various formulations of the compositions including creams, lotions, ointments and sprays are disclosed for use in accordance with this invention. The compositions and formulations may contain additional active ingredients.

REFERENCES:
patent: 3655881 (1972-04-01), Jackon
patent: 3966777 (1976-06-01), Mazur et al.
patent: 4230701 (1980-10-01), Holick et al.
patent: 4308264 (1981-12-01), Conway et al.
patent: 4435325 (1984-03-01), Jolly et al.
Van de Kerkhof et al., British J. Dermatol., 120:661-664 (1989).
Morimoto et al., British J. Dermatol., 115:421-429 (1986).
Kato et al., British J. Dermatol., 115:431-433 (1986).
Smith et al., J. Amer. Acad. Dermatol., 19(3):516-528 (Sep. 1988).
Kragballe et al., British J. Dermatol., 119:223-230 (1988).
Chemical Abstracts 84:53879j, 1976 (Popovici).
Wells, Amer. Perf. & Essen, Oil Review, pp. 117 and 120, (1953).

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