Compositions containing 1,2,3,4-tetrahydroisoquinolines used as

Details Compositions containing 1,2,3,4-tetrahydroisoquinolines used as Compositions containing 1,2,3,4-tetrahydroisoquinolines used as

1972-12-11

1977-05-10

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3147

Patent

active

040229009

ABSTRACT:
Disclosed are 5,6,7 or 8-nuclear substituted benzamido-1,2,3,4-tetrahydroisoquinolines of the formula ##STR1## in which R is a phenyl containing one to three hydroxyl, nitro, halo, lower alkyl or lower alkoxy groups, and R.sub.1 is hydrogen or a lower alkyl. The compounds lower blood pressure in animals.

REFERENCES:
patent: 3022308 (1962-02-01), Cavallito
patent: 3674791 (1972-07-01), Mathison
Lusinchi et al., C.A. 53:21946-21947 (1959).
Beeby et al., C.A. 44:1510 (1956).

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