Compositions comprising tissue specific adenoviral vectors

Chemistry: molecular biology and microbiology – Vector – per se

Reexamination Certificate

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C424S093100, C424S093200, C424S093600, C435S235100, C435S069100, C536S023100, C536S023720, C536S024100

Reexamination Certificate

active

07001764

ABSTRACT:
Compositions comprising host cell specific adenovirus vehicles are provided for transfecting target host cells. The compositions comprise replication competent adenovirus having an adenovirus gene essential for replication under transcriptional control of a cell type specific transcriptional response element (TRE) and polyethylene glycol (PEG) as a masking agent.

REFERENCES:
patent: 5698443 (1997-12-01), Henderson et al.
patent: 5871726 (1999-02-01), Henderson et al.
patent: 5998205 (1999-12-01), Hallenbeck et al.
patent: 6197293 (2001-03-01), Henderson et al.
patent: 6254862 (2001-07-01), Little et al.
patent: 6676935 (2004-01-01), Henderson et al.
patent: WO 96/14874 (1996-05-01), None
patent: WO96/17053 (1996-06-01), None
patent: WO 96/21036 (1996-07-01), None
patent: WO97/01358 (1997-01-01), None
Berkner and Sharp, “Generation of adenovirus by transfection of plasmids”, (1983),Nucleic Acid Research, 11(17): 6003-6020.
Bett et al., “An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3”, (1994),Proc. Natl. Acad. Sci.,91:8802-8806.
Bett et al., “Packaging capacity and stability of human adenovirus type 5 vectors”, (1993),J. Virology, 67(10):5911-5921.
Croyle et al., “Development of a Rapid Method for the PECylation of Adenoviruses with Enhanced Transduction and Improved Stability under Harsh Storage Conditions”, (2000), Human Gene Therapy, 11:1713-1722.
Graham, “Growth of 293 cells in suspension culture”, (1987),J. Genetic Virology, 68:937-940.
Graham, “Covalently closed circles of human adenovirus DNA are infectious”, (1984),EMBO. J., 3(12):2917-2922.
Graham et al., “Characteristics of a human cell line transformed by DNA from human adenovirus type 5”, (1977),J. Gen. Virol., 38:59-72.
Graham et al., “A new technique for the assay of infectivity of human adenovirus 5 DNA”, (1973),Virology, 52:456-467.
Hayashi et al., “Expression of a thyroid hormone-responsive recombinant gene introduced into adult mice livers by replication-defective adenovirus can be regulated by endogenous thyroid hormone receptor”, (1994),J. Biol. Chem., 269:23872-23875.
Jaffe et al., “Adenovirus-mediated in vivo gene transfer and expression in normal rat liver”, (1992),Nat Gent., 1:372-378.
Le Gal La Salle et al., “An adenovirus vector for gene transfer into neurons and glia in the brain”, (1993),Science, 259:988-990.
Mastrangeli et al., “Diversity of airway epithelial cell targets for in vivo recombination adenovirus-mediated gene transfer”, (1993),J. Clin. Invest., 91:225-234.
Quantin et al., “Adenovirus as an expression vector in muscle cells in vivo”, (1992),Proc Natl. Acad. Sci., 89:2581-3584.
Ragot et al., “Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice”, (1993),Nature, 361:647-650.
Rosenfeld, “Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo”, (1991), Science, 252:431-434.
Rosenfeld et al., “In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium”, (1992),Cell, 68:143-155.
Stratford-Perricaudet, “Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector”, (1990),Human Gene Therapy, 1:241-256.
Stratford-Perricaudet et al., “Widespread long term gene transfer to mouse skeletal muscles and heart”, (1992),J. Clin. Invest. 90:626-630.
Takiff et al., “Propagation and in vitro studies of previously non-cultivable enteral adenoviruses in 293 cells”, (1981),Lancet, 11:832-834.
Wang et al., “Expression of the APRT gene in an adenovirus vector system as a model for studying gene therapy”, (1991),Adv. Exp. Med. Biol., 309:61-66.

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