Drug – bio-affecting and body treating compositions – Lymphokine
Reexamination Certificate
2007-05-01
2007-05-01
O'Hara, Eileen B. (Department: 1646)
Drug, bio-affecting and body treating compositions
Lymphokine
C514S169000, C514S171000, C514S002600, C530S351000
Reexamination Certificate
active
10728383
ABSTRACT:
The present invention provides a composition comprising (i) a compound comprising a sulphamate group (“a sulphamate compound”); and (ii) an apoptosis inducer.
REFERENCES:
patent: 5350836 (1994-09-01), Kopchick et al.
patent: 6339079 (2002-01-01), Kasch et al.
patent: WO 97/01633 (1997-01-01), None
patent: WO 99/64013 (1999-12-01), None
patent: 2000/66095 (2000-11-01), None
patent: WO 00/66095 (2000-11-01), None
patent: 2002/16394 (2002-02-01), None
patent: 2004/085459 (2004-10-01), None
Gura, T. Science, vol. 278, Nov. 1997, pp. 1041-1042.
Gerald Dermer, Bio/Technology, Mar. 1994, vol. 12, p. 320.
Rakesh Jain, Science, Feb. 23, 1996, vol. 271.
Rakesh Jian, Cancer and Metastasis Revies, 1990, vol. 9, pp. 253-266.
Francklyn, C., Aminoacyl-tRNA Synthetases: Versatile Players in the Changing Theater of Translation, RNA, vol. 8, pp. 1363-1372 (2002).
Goodman & Gilman's The Pharmacological Basis of Therapeutics, 9th Ed., McGraw-Hill, NY, (1996).
Nagase, H., et al., The Pharmacological Profile of δ Opioid Receptor Ligands, (+) and (−) TAN-67 on Pain Modulation, Life Sciences, vol. 68, pp. 2227-2231 (2001).
Kick, E.K., et al., Structure-Based Design and Combinatorial Chemistry Yield Low Nanomolar Inhibitors of Cathepsin D, Chemistry & Biology, vol. 4, No. 4, pp. 297-307 (1997).
Elger, W., et al., J. Ster. Biochem. Molec. Biol. 55 (1995) 395-403.
MacCarthy, L. et al., “Differential Effects of Estrone and Estrone-3-O-Sulfamate Derivatives on Mitotic Arrest, Apoptosis, and Mirctubule Assembly in Human Breast Cancer Cells,”Cancer Research, 60: 5441-50, 2000 (XP-001031282).
Pitti, R. et al., “Induction of Apoptosis by Apo-2-Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family,”Journal of Biological Chemistry, 271(22): 12687-90, 1996 (XP-002031265).
Purohit, A. et al., “The Development of A-ring Modified Analogues of Oestrone-3-O-sulphamate as Potent Steroid Sulphatase Inhibitors with Reduced Oestrogenicity,”J. Steroid Biochem. Molec. Biol., 64(5-6): 269-75, 1998 (XP-000852539).
Purohit, A. et al., “The Effect of 2-Methoxyoestrone-3-O-Sulphamate on the Growth of Breast Cancer Cells and Induced Mammary Tumours,”Int. J. Cancer, 85: 584-89, 2000 (XP-001039923).
Spyridopoulos, I. et al., “Restoration of E2F Expression Rescues Vascular Endothelial Cells from Tumor Necrosis Factor-α-Induced Apoptosis,”Circulation, 98:2883-90, 1998 (XP-002214772).
Wiley, S. et al., “Identification and Characterization of a New Member of the TNF Family that Induces Apoptosis,”Immunity, 3: 673-82, 1995 (XP-000672297).
Reed, M.J. et al. “Steroid Sulfatase: Molecular Biology, Regulation and Inhibition.” Endocrine Reviews2005; 26:171-202.
Lloyd Potter Barry Victor
Packham Keith Graham
Reed Michael John
Collison Angela M.
Kowalski Thomas J.
O'Hara Eileen B.
Sterix Limited
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