Compositions comprising lipoproteins and crotonamide derivatives

Details Compositions comprising lipoproteins and crotonamide derivatives Compositions comprising lipoproteins and crotonamide derivatives

1996-12-10

1998-07-14

Tsang, Cecilia J.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Lipoproteins, e.g., egg yolk proteins, cylomicrons, etc.

514 2, 514378, 514464, 514465, 514521, 514522, 4242831, 549439, 558392, C07K 100, A61K 3142, A61K 31275

Patent

active

057805920

ABSTRACT:
A composition comprising lipoproteins and a compound of the formula I ##STR1## stereoisomeric form or salt thereof, suitable for the treatment of immunological disorders, cancer or in transplantation.

REFERENCES:
patent: 4061767 (1977-12-01), Ertel et al.
patent: 5240960 (1993-08-01), Hambleton et al.
patent: 5308865 (1994-05-01), Bartlett et al.
patent: 5384423 (1995-01-01), Hambleton et al.
Ananth et al., "Apolipoproteins A-I and B and Cholesterol in Synovial Fluid of Patients With Rheumatoid Arthritis", Metabolism, 42(7):803-806 (Jul. 1993).
Schorlemmer et al., "Therapeutic activity of leflunomide in acute and chronic relapsing experimental allergic encephalomyelitis", Agents Action 41, Special Conference Issue: C271-C273 (1994).
Garton et al., "Pseudosepsis in Rheumatoid Arthritis due to Cellular and Lipid Abnormalities in Synovial Fluid", British J. of Rheumatology, 31:625-626 (1992).
Q. Xu et al., "Lipid utilization by human lymphocytes is correlated with high-density-lipoprotein binding site activity", Biochem. J., 285:105-112 (1992).
Biochemie der Lipoproteine, pp. 15-31 and 44-53 (In German) (date is not available).

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