Compositions comprising hypsizygus ulmarius extract

Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...

Reexamination Certificate

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C514S886000, C424S756000

Reexamination Certificate

active

07575764

ABSTRACT:
Disclosed are topical compositions comprising extracts ofHypsizygus ulmariusin amounts that are effective to influence LTB4-mediated chemotaxis and/or IL-1β mediated adhesion of polymorphonuclear leukocytes. Thehypsizygus ulmariusextract may be used alone or in combination with secondary anti-inflammatory and skin active agents, such as other mushroom and/or natural extracts. The secondary anti-inflammatory agents may or may not function by antagonizing LTB4-mediated chemotaxis and IL-1β mediated adhesion. The extract may be incorporated into a cosmetically acceptable vehicle. The present invention includes methods of treating skin inflammation by applying to inflamed skin, anti-inflammatory effective amounts ofHypsizygus ulmariusextract in a defined treatment regimen.

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