Compositions comprising hyaluronic acid and prostaglandin-synthe

Brushing – scrubbing – and general cleaning – Machines – Brushing

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 23, 514 62, 536 53, 536 552, 536 88, 5361231, A61K 31715, A61K 31725

Patent

active

057927537

ABSTRACT:
A topically administrable pharmaceutical composition is disclosed which comprises a therapeutically effective amount of a drug which inhibits prostaglandin synthesis, and an amount of a form of hyaluronic acid sufficient to transport the composition through the skin into the epidermis or dermis where the composition remains until discharged via the lymphatic system, wherein

REFERENCES:
patent: 2583096 (1952-01-01), Hadidian et al.
patent: 3042667 (1962-07-01), Flodin et al.
patent: 3357784 (1967-12-01), Kasper et al.
patent: 3396081 (1968-08-01), Billek et al.
patent: 3436454 (1969-04-01), Nouvel
patent: 3792164 (1974-02-01), Bechtold et al.
patent: 3845201 (1974-10-01), Haddad et al.
patent: 3870791 (1975-03-01), Haddad et al.
patent: 3887703 (1975-06-01), Manoussos et al.
patent: 4003991 (1977-01-01), Krohn et al.
patent: 4045558 (1977-08-01), Smith et al.
patent: 4061722 (1977-12-01), Bodor et al.
patent: 4141973 (1979-02-01), Balazs
patent: 4240163 (1980-12-01), Galin
patent: 4255415 (1981-03-01), Chrai et al.
patent: 4271143 (1981-06-01), Schoenwald et al.
patent: 4272522 (1981-06-01), Balazs
patent: 4280954 (1981-07-01), Yannas et al.
patent: 4303676 (1981-12-01), Balazs
patent: 4328803 (1982-05-01), Pape
patent: 4470975 (1984-09-01), Berger, deceased et al.
patent: 4478822 (1984-10-01), Haslam et al.
patent: 4487865 (1984-12-01), Balazs et al.
patent: 4500676 (1985-02-01), Balazs
patent: 4517295 (1985-05-01), Bracke
patent: 4582865 (1986-04-01), Balazs et al.
patent: 4629623 (1986-12-01), Balazs et al.
patent: 4636524 (1987-01-01), Balazas et al.
patent: 4684627 (1987-08-01), LeVeen et al.
patent: 4686288 (1987-08-01), Lormeau et al.
patent: 4711780 (1987-12-01), Fahim
patent: 4713448 (1987-12-01), Balazs et al.
patent: 4716224 (1987-12-01), Sakurai et al.
patent: 4725585 (1988-02-01), Wenge et al.
patent: 4736024 (1988-04-01), Della Valle et al.
patent: 4746504 (1988-05-01), Nimrod et al.
patent: 4755544 (1988-07-01), Makino et al.
patent: 4782046 (1988-11-01), Brown et al.
patent: 4784990 (1988-11-01), Nimrod et al.
patent: 4784991 (1988-11-01), Nimrod et al.
patent: 4795741 (1989-01-01), Leshchiner et al.
patent: 4801619 (1989-01-01), Lindblad
patent: 4804537 (1989-02-01), Bergman et al.
patent: 4808576 (1989-02-01), Schultz et al.
patent: 4814175 (1989-03-01), Tack et al.
patent: 4814176 (1989-03-01), Makino et al.
patent: 4840941 (1989-06-01), Ueno et al.
patent: 4851521 (1989-07-01), della Valle et al.
patent: 4853224 (1989-08-01), Wong
patent: 4853226 (1989-08-01), Machida et al.
patent: 4855134 (1989-08-01), Yamahira et al.
patent: 4863907 (1989-09-01), Sakurai et al.
patent: 4877619 (1989-10-01), Richer
patent: 4879282 (1989-11-01), Saliba, Jr.
patent: 4912093 (1990-03-01), Michaeli
patent: 4913898 (1990-04-01), Altobelli et al.
patent: 4937254 (1990-06-01), Sheffield et al.
patent: 4937270 (1990-06-01), Hamilton et al.
patent: 4944941 (1990-07-01), Ammann
patent: 4946870 (1990-08-01), Partain, III et al.
patent: 4957744 (1990-09-01), della Valle et al.
patent: 4963666 (1990-10-01), Malson
patent: 4965353 (1990-10-01), della Valle et al.
patent: 4970298 (1990-11-01), Silver et al.
patent: 5095037 (1992-03-01), Iwamitsu et al.
patent: 5166331 (1992-11-01), della Valle et al.
Sandra Blakeslee, "Solid cores of tumors keeping out best drugs", Jul. 8, 1989 edition of the Globe and Mail, Toronto, Ontario, p. D4.
Pam Harrison, "Toxic drug tamed but still potent" Ontario Medicine, vol. 8, No. 16 dated Aug. 21, 1989, p. 1.
The Merck Index Eleventh Edition, Centennial Edition, Hyaluronic Acid formulation, pp. 751 and 752, 1989.
Alan R. Liss, Inc., Modulation of Immunity in Cancer Patients by Prostaglandin Antagonists, Immunity to Cancer II, Braun et al. pp. 439-448, 1989.
Goodwin, J.S. Prostaglandin E and Cancer Growth Potential for Immunotherapy with Prostaglandin Synthesis Inhibitors, Augmentive Agents in Cancer Therapy, Raven Press, New York, (1981).
Dr. Samuel Asculai, "Inactivation of Herpes Simplex Viruses by Nonionic Surfactants", Antimicrobial Agents and Chemotherapy, Apr. 1978, pp. 686-690.
Chemical Abstracts, vol. 76, No. 10; W. E. Sneader; "Possible Mechanism for action of DMSO on Percutaneous absorption", J. Pharm. Pharmcol, 1971, 23 (Supp).
Alaverdyan MI, Ter-Avetisyan AT. Effect of hyaluronidase, hyaluronic acid, and some other substances on postradiational experimental bacteriemai. Bulletin of Experimental Biology and Medicine 1967; 64(9):967-969.
Balazs EA, Gibbs DA. The rheological properties and biological function of hyaluronic acid. In: Chemistry and Molecular Biology of the Intercellular Matrix. vol. III. New York: Academic Press, 1970. pp. 1241-1253.
Balazs EA, Band P. Hyaluronic acid: Its structure and use. Cosmetics & Toiletries. Polymers in Cosmetics 1984; 99; 65-72.
Camber O, Lundgren P. Diffusion of some low molecular weight compounds in sodium hyaluronate. Acta Pharmaceutica Suecica 1985; 22(6):315-320.
Camber O, Edman P, Gurny R. Influence of sodium hyaluronate on the meiotic effect of pilocarpine effect in rabbits. Current Eye Research 1987: 6(6):779-784.
Chang S-C. Pro-drug and vehicle approaches to improve the therapeutic index of topically applied timolol in the pigmented rabbit. Dissertation Abstracts International 1988; 49(2) 367-B.
Cravioto, R.O. et al. Effects of Precipitates Formed by Insulin with Hyaluronic Acid and Mucoid From Vitreous Humor in Depressing Blood-Sugar Levels Science (1950): vol. 111:520-521.
Gieldanowski, Jerzy: Skowronska, Jadwiga Studies on immunosuppressive and anti-inflammatory effect of adriamycin. Arch. Immunol. Ther. Exp. (1980); 28 (3):439-446.
Hassan HG, Akerman B, Ranck H, Lindberg B, Lindquist B. Effects of adjuvants to local anaesthetics on their duration. Acta Anaesthesiol. Scand. 1985; 29:384-388.
Hurd ER Immunosuppresive and anti-inflammatory properties of cyclophosphamide, azathioprine and methotrexate. Arthritis and Rheumatism (1973 Jan.-Feb.); 16 (1):84-88.
Idson B. Polymers in skin cosmetics. Cosmetics & Toiletries 1988; 103:63-68.
Johansson A, Hassan H, Renck H. Effects of adjuvants to local anaesthetics on their duration. Acta Anaesthesiol. Scand. 1985; 29:736-738.
Kalbhen D.A. The inhibitory effects of steroidal and non-steroidal antirheumatic drugs on articular cartilage in osteoarthrosis and its counteraction by a biological GAG-peptide complex (Rumalon.RTM.). Z. Rheumatol (1982); 41:202-211.
Katsu M., Abe T., Shimada S. Significance and clinical use of non-steroid anti-inflammatory drugs as substitutes for steroids in steroid dependence. Nippon Rinsho (1968 Jan); 26(1):89-95.
Kreis H, Chkoff N, Droz D, et al. Nonsteroid anti-inflammatory agents as a substitute treatment for steroids in ATGAM-treated cadaver kidney recipients. Transplantation (1984 Feb.); 37(2): 139-145.
McIlwraith W. Current concepts in equine degenerative joint disease. Journal of the American Veterinary Medical Association 1982; Feb. 1:239-250.
Mizushima, Y. Possibility of non-steroid anti-inflammatory drugs as a substitute for steroids-analysis of the present situation and demands for the future. Nippon Rinsho (Jan. 1986); 26(1): 61-65.
Nizolek DJH, White KK. Corticosteroid and hyaluronic acid treatments in equine degenerative joint disease: A review. The Cornell Veterinarian 1981; 71(4):355-375.
Pigman W, et al. Acide hyaluronique et facteurs de permeabilite tissulaire. Bull. Soc. Chim. Biol. 1963; 45(2-3):185-202.
Pruett RC, Schepens CL, Constable IJ, Swann DA. Hyaluronic acid vitreous substitute. In: Vetreous Surgery and Advances in Fundus Diagnosis and Treatment. Freeman H.M., et al., Editors. Appleton-Century-Crofts, 1977: Chapter 55, pp. 433-444.
Reim M. Teping C. Surgical procedures in the treatment of most severe eye burns. Acta Ophthalmologica 1989-Supplementum 192; 67:47-54.
Rydell NW, Balazs EA. Effect of intra-articular injection of hyaluronic acid on the clinical symptons of osteoarthritis and on granulation tissue formation. Clinical Orthopaedics and Related Research 1971; 80(Oct.):25-29.
Saba P, Galeone F, Salvadorini F. Guarguaglini M, Ombrato M. Investigation of the antihyperlipemic activity of an associ

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compositions comprising hyaluronic acid and prostaglandin-synthe does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions comprising hyaluronic acid and prostaglandin-synthe, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions comprising hyaluronic acid and prostaglandin-synthe will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-389081

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.