Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2011-07-12
2011-07-12
Robinson, Hope A (Department: 1652)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S380000, C530S350000, C530S300000, C514S002600, C514S012200
Reexamination Certificate
active
07977460
ABSTRACT:
The present invention relates to the use of FIXa and FVIII in the preparation of a composition for the treatment of haemophilia A or haemophilia B in a subject which does not present with anti-FVIII antibodies. The present invention further relates to a composition comprising FIXa and a composition comprising FVIII for simultaneous, simultaneous separate or sequential use in the treatment of haemophilia A or haemophilia B in a subject which does not present with anti-FVIII antibodies.
REFERENCES:
patent: 4348384 (1982-09-01), Horikoshi et al.
patent: 4459288 (1984-07-01), Thomas
patent: 4501731 (1985-02-01), Tishkoff et al.
patent: 4965199 (1990-10-01), Capon et al.
patent: 4994371 (1991-02-01), Davie et al.
patent: 5506112 (1996-04-01), Lang et al.
patent: 5839443 (1998-11-01), Rose et al.
patent: 5925739 (1999-07-01), Spira et al.
patent: 5972885 (1999-10-01), Spira et al.
patent: 6013620 (2000-01-01), Turecek et al.
patent: 2003/0203845 (2003-10-01), Knudsen et al.
patent: 2 125 409 (1984-03-01), None
patent: WO 88/00210 (1988-01-01), None
patent: WO 01/27079 (2001-04-01), None
Elodi et al., Optimization and conditions for the catalytic effect of the factor IXa-factor VIII complex, Thrombosis Research 15, p. 617-629, (1979).
Barry et al., Proteolytic interactions of factor IXa with human factor VIII and factor VIIIa, Blood, vol. 80, No. 12 (Dec. 15, 1992).
T. W. Barrowcliffe, et al., Binding To Phospholipid Protects Factor VIII From Inactivation By Human Antibodies. J. Lab. Clin. Med., Jan. 1983, vol. 101, No. 1, p. 34-43.
Karin Fijnvandraat, et al., A Human Alloantibody Interferes With Binding Of Factor IXa To The Factor VIII Light Chain, Blood, Apr. 1, 1998, vol. 91, No. 7, p. 2347-2352.
Abstract 2028: Eva H. N. Olsen, et al., Cross-Linking Of Three Factor VIII Peptides To Factor IXa: Support For Multiple Domain Interactions Between Factor IXa And Its Cofactor. Poster Board # Session: 257-III.
L. M. Aledort, Is The Incidence And Prevalence Of Inhibitors Greater With Recombinant Products? Yes, Journal Of Thrombosis and Haemostasis ((2004) vol. 2, p. 861-862.
R. G. Di Scipio, et al., Activation Of Human Factor IX (Christmas Factor), J. Clin. Inves. (1978) vol. 61, No. 6, p. 1528-1538.
David Gailani, Activation Of Factor IX By Factor XIa, TCM (2000) vol. 10, No. 5, p. 198-204.
I. Hvid, et al., Orthopaedic Surgery In Haemophilic Patients With Inhibitors: An Overview, Haemophilia (2002) vol. 8, p. 288-291.
Barry J. Lamphear, et al., Proteolytic Interactions Of Factor IXa With Human Factor VIII And Factor VIIIa, Blood (1992) vol. 80, No. 12, p. 3120-3126.
J.H. McIntosh, et al., A Modified Thrombin Generation Test For The Measurement Of Factor VIII Concentrates, Journal of Thrombosis and Haemostasis, vol. 1, p. 1-7.
J. Wright, et al., The Epidemiology Of Inhibitors In Haemophilia A: A systematic Review, Haemophilia (2003) vol. 9, p. 418-435.
Abstract: M. Shima, et al., The Current Situation And Vision Of Plasma Protein Formulation . . . , Biomedical Perspectives (1999) vol. 8, No. 1, p. 99-107.
Abstract: A. Yoshioka, Recombinant Factor VIII, 8. Recombinant Factor VIII Formuation, Jap. J. Transfus. Med. (1992) vol. 38, No. 6, p. 845-849.
Abstract: M. Arai, The Current Situation And Vision Of Plasma Protein . . . ; Biomed. Perspect. (1999) vol. 9, No. 1, p. 108-117.
Kowalski Thomas J.
Lu Deborah L.
National Institute for Biological Standards and Control
Robinson Hope A
Vedder Price P.C.
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