Compositions comprising antigen-complexes, method of making...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector

Reexamination Certificate

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C424S009100, C424S009200, C424S193100, C424S204100, C424S234100, C424S278100

Reexamination Certificate

active

07491395

ABSTRACT:
The present invention provides methods and means for preparing vaccines that are capable of eliciting strong immune responses, especially through intranasal delivery. The invention discloses particles, referred to as “co-micelles,” in which antigens are present that interact through hydrophobic interactions with certain specific types of amphiphilic compounds, wherein the amphiphilic compounds have adjuvant activity and wherein the antigens are preferably antigenic surface proteins, such as integral membrane proteins from infectious agents like viruses.

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