Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-01-11
2011-01-11
Carlson, Karen Cochrane (Department: 1652)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S018000, C436S800000, C570S101000, C523S500000, C549S223000, C549S384000
Reexamination Certificate
active
07867726
ABSTRACT:
A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein.
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Bulleit Robert F.
Klaubert Dieter
Los Georgyi V.
McDougall Mark
Wood Keith V.
Carlson Karen Cochrane
Casimir Jones S.C.
Kosson Rosanne
Promega Corporation
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