Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Matrices
Reexamination Certificate
2005-04-28
2011-11-29
Krass, Frederick (Department: 1612)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Matrices
C523S105000, C523S111000
Reexamination Certificate
active
08067031
ABSTRACT:
Crosslinkable compositions are provided that readily crosslink in situ to provide crosslinked biomaterials. The composition contains at least two biocompatible, non-immunogenic components having reactive groups thereon, with the functional groups selected so as to enable inter-reaction between the components, i.e., crosslinking. In one embodiment, a first component has nucleophilic groups and a second component has electrophilic groups. Additional components may have nucleophilic or electrophilic groups. Methods for preparing and using the compositions are also provided as are kits for delivery of the compositions. Exemplary uses for the crosslinked compositions include tissue augmentation, biologically active agent delivery, bioadhesion, and prevention of adhesions following surgery or injury.
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pa
Daniloff George Y.
Gravett David M.
Schroeder Jacqueline
Sehl Louis C.
Toleikis Philip M.
AngioDevice International GmbH
Krass Frederick
Seed IP Law Group PLLC
Sutton Darryl C
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