Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1974-07-18
1976-10-19
Drezin, Norman A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
A61K 31275
Patent
active
039871924
ABSTRACT:
This invention relates to pharmaceutical compositions containing known compounds of the formula ##SPC1##
Wherein M is selected from the group consisting of hydrogen, aluminum, ammonium, sodium, potassium, calcium, tris(hydroxymethyl)methylammonium and lower alkyl of 1 through 4 carbon atoms, R is selected from the group consisting of hydrogen and lower alkyl of 1 through 4 carbon atoms, and R.sub.1 and R.sub.2 are selected from the group consisting of hydrogen, fluorine, chlorine, bromine, trifluoromethyl, lower alkoxy of 1 through 4 carbon atoms and lower alkyl of 1 through 4 carbon atoms.
The compounds (1) above are formulated with pharmaceutical carriers for inhalation or for oral, parenteral or rectal administration, with insufflation being the preferred method. The compositions are useful in the prophylactic treatment of sensitized humans and mammals for allergic and all anaphylactic reactions of a reaginmediated and non-reagin-mediated nature.
REFERENCES:
patent: 3852324 (1974-12-01), Wright
patent: 3864493 (1975-02-01), Cairns et al.
patent: 3879544 (1975-04-01), Reisner et al.
patent: 3883653 (1975-05-01), Barth
patent: 3885038 (1975-05-01), Pfister et al.
Bogert et al., Chemical Abstracts 5:82.sup.7.
Reissert et al., Chemical Abstracts 4:206.sup.4.
Berichte 42: 3710-3721 (1909).
Ciba Ltd., Chemical Abstracts 72:12413m (1970).
Barancik Martin B.
Drezin Norman A.
Hodes William A.
Saliwanchik Roman
The Upjohn Company
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