Compositions and methods using RNA interference for control...

Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...

Reexamination Certificate

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C800S285000

Reexamination Certificate

active

07622301

ABSTRACT:
The present invention concerns double stranded RNA compositions and transgenic plants capable of inhibiting expression of essential genes in parasitic nematodes, and methods associated therewith. Specifically, the invention relates to the use of RNA interference to inhibit expression of a target essential parasitic nematode gene selected from the group consisting of a parasitic nematode cytosolic chaperonin gene, a parasitic nematode gene encoding heat shock protein-90, a parasitic nematode gene homologous to theC. elegansY65B4BR.5a gene, and a parasitic nematode gene homologous to aC. eleganspat-10 gene, and relates to the generation of plants that have increased tolerance to parasitic nematodes.

REFERENCES:
patent: 5589622 (1996-12-01), Gurr et al.
patent: 5824876 (1998-10-01), Gurr et al.
patent: 6506559 (2003-01-01), Fire et al.
patent: 6521438 (2003-02-01), Davis et al.
patent: 6753139 (2004-06-01), Baulcombe et al.
patent: 6784337 (2004-08-01), Atkinson et al.
patent: 2002/0086356 (2002-07-01), Tuschl et al.
patent: 2003/0150017 (2003-08-01), Mesa et al.
patent: 2003/0235898 (2003-12-01), Kloek et al.
patent: 2004/0091467 (2004-05-01), Williams et al.
patent: 2004/0098761 (2004-05-01), Trick et al.
patent: 2004/0133943 (2004-07-01), Plaetinck et al.
patent: 2005/0091713 (2005-04-01), Atkinson et al.
patent: 0983370 (2003-09-01), None
patent: 1080208 (2005-03-01), None
patent: WO 99/53050 (1999-10-01), None
patent: WO 01/37654 (2001-05-01), None
patent: WO 01/96584 (2001-12-01), None
patent: WO 03/052110 (2003-06-01), None
patent: WO 2004/005485 (2004-01-01), None
Terami et al., J. Cell Biol. 1999, vol. 146, pp. 193-202.
Yan et al., GenBank Accession No. AF249890, Jul. 12, 2000.
Leroux, MR, “Characterization of four new tcp-1-related cct genes from the nematode Caernorhabditis elegans.,” DNA Cell Biol., Nov. 1995, pp. 95-60, 14(11), Abstract Only.
Hammond et al., “Post-transcriptional gene silencing by double-stranded RNA,” Nature Reviews, Feb. 2001, pp. 110-119, vol. 2.
Bass, BL, “The short answer,” Nature, May 24, 2001, pp. 428-429, vol. 411.
Elbashir et al., “Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells,”Nature, May 24, 2001, pp. 494-498, vol. 411.
Wesley et al., “Construct design for efficient, effective and high-throughput gene silencing in plants,” The Plant Journal, 2001, pp. 581-590, 27:6.
Bass, BL, “Double-stranded RNA as a template for gene silencing,” Cell, Apr. 28, 2000, pp. 235-238, vol. 101.
Birnby et al., “A transmembrane Guanylyl Cyclase (DAF-11) and Hsp90 (DAF-21) regulate a common set of chemosensory behaviors in . . . ” Genetics, May 2000, pp. 85-104, vol. 155.
Young LD, “Managing soybean resistance to heterodera glycines,” Suppl. to Journal of Nematology, 1998, pp. 525-529, vol. 30:4S.
Davis et al., “Nematode parasitism genes,” Annu. Rev. Phytopathol., Sep. 2000, pp. 341-372, vol. 38.
Boutla et al., “Induction of RNA interference in Caenorhabditis elegans by RNAs derived from plants exhibiting . . . ,” Nucleic Acids Res., 2002, pp. 1688-1694, 30:7.
Urwin et al., “Ingestion of double-stranded RNA by preparasitic juvenile cyst nematodes leads to RNA interference,”MPMI, 2002, pp. 747-752, 15:8.
Leroux et al., “Characterization of C. elegans CCT, a hetero-oligomeric cytosolic chaperonin containing two related proteins, CCT-1 . . . ,” Early 1995 Int'l Worm Mtg. Abstract.
Goenczy et al., “Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III,” Nature, Nov. 16, 2000, 331-336, 408.
Kamath et al., “Systematic functional analysis of the Caenorhabditis elegans genome using RNAi,” Nature, Jan. 16, 2003, 231-237, 421.
Gao et al., “Identification of Putative Parasitism Genes Expressed in the Esophageal Gland Cells of the Soybean Cyst Nematode Heterodera . . . ” MPMI, 2001, pp. 1247-1254, 14.
Database UniProt ′Online!, Chaperonin containing tcp-1 protein 6, isoform b. XP002328417 retrieved from EBI accession No. UniProt:Q8MYQ9, Oct. 1, 2002.
Atkinson et al., “Engineering Plants for Nematode Resistance,” Annu. Rev. Phytopathol., 2003, 615-639, 41.
Simmer et al., “Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions,” 2003, PloS Biology, 1(1), pp. 77-84.
David P. Bartel, “MicroRNAs: Genomics, Biogenesis, Mechanism, and Function”, journal, Jan. 23, 2004, Cell, vol. 116, 281-297, Cell Press, Cambridge, Massachusetts.
Yukio Kurihara and Yuichiro Watanabe, “Arabidopsis micro-RNA biogenesis through Dicer-like 1 protein functions”, journal, Aug. 24, 2004, 12753-12758, vol. 101, No. 34, PNAS.

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