Compositions and methods useful for genetic analysis

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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4353201, 436501, 436 94, 536 2431, 935 77, 935 78, C12Q 168, G01N 3348, G01N 33566, C07H 1512

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052061370

ABSTRACT:
A method for obtaining polynucleotide sequences which are useful for detecting Variable Tandem Repeat polymorphism at multiple genetic loci and other genetic analyses under high stringency conditions (hence, with high specificity) is herein disclosed. Also disclosed are polynucleotide sequences and other compositions useful for DNA polymorphism and other genetic analyses.

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Baird, M., I. Balazs et al. (1986) "Allele Frequency Distribution of Two Highly Polymorphic DNA Sequences in Three Ethnic Groups and Its Application to the Determination of Paternity," Am. J. Hum. Genet. 39:489-501.
Nakamura, Y., M. Leppert et al. (1987) "Variable Number of Tandem Repeat (VNTR) Markers for Human Gene Mapping," Science 235:1616-1622.
Jeffreys, A. J., V. Wilson, S. L. Thein (1985) "Hypervariable `minisatellite` regions in human DNA," Nature 314:67-73.

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