Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Fusion of cells
Reexamination Certificate
2008-07-29
2008-07-29
Hartley, Michael G. (Department: 1618)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Fusion of cells
C607S001000, C424S450000, C424S400000
Reexamination Certificate
active
07405080
ABSTRACT:
The present invention relates to a method for protecting a human patient or a mammalian animal to be subjected to chemotherapy treatment of a tumor not residing in the scalp of the patient or the skin of the animal against chemotherapy-induced alopecia, comprising administering to the scalp of the patient or the skin of the animal an effective amount of a composition comprising a chemical inducer of the stress protein response sufficiently prior to the administration of a chemotherapeutic drug. It also relates to pharmaceutical compositions for the prevention of chemotherapy-induced alopecia. It further relates to a method for protecting a human patient or a mammalian animal to be subjected to chemotherapy treatment of a tumor not residing in the scalp of the patient or the skin of the animal against chemotherapy-induced alopecia, comprising administering to the scalp of the patient or the skin of the animal an effective heat dose sufficiently prior to the administration of a chemotherapeutic drug.
REFERENCES:
patent: 5486509 (1996-01-01), Jimenez et al.
patent: 5830177 (1998-11-01), Li et al.
patent: 3724259 (1989-02-01), None
patent: WO 98/15281 (1998-04-01), None
patent: WO 98/46208 (1998-10-01), None
International Search Report for PCT/IB01/01607.
Hartley Michael G.
Rogers Jim
Saliwanchik Lloyd & Saliwanchik
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