Compositions and methods of using chondroitinase ABCI mutants

Details Compositions and methods of using chondroitinase ABCI mutants Compositions and methods of using chondroitinase ABCI mutants

2008-12-18

2010-06-08

Raghu, Ganapathirama (Department: 1652)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Transferases

C424S094620, C435S232000, C435S200000, C435S018000, C536S023200

Reexamination Certificate

active

07731956

ABSTRACT:
One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.

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