Compositions and methods of using chondroitinase ABCI mutants

Details Compositions and methods of using chondroitinase ABCI mutants Compositions and methods of using chondroitinase ABCI mutants

2006-09-26

2009-02-03

Prouty, Rebecca E. (Department: 1652)

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

C424S094620, C435S200000, C536S023200

Reexamination Certificate

active

07485295

ABSTRACT:
One aspect of the present invention relates to mutants of chondroitinase ABCI. Such chondroitinase ABCI mutants exhibit altered chondroitin lyase activity or increased resistance to inactivation from stressors including exposure to UV light or heat. Methods of using chondroitinase ABCI mutant enzymes are also provided.

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