Compositions and methods of use of EPB1, and ErbB3 binding...

Details Compositions and methods of use of EPB1, and ErbB3 binding... Compositions and methods of use of EPB1, and ErbB3 binding...

2008-04-25

2010-11-23

Canella, Karen A (Department: 1643)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S021800, C514S04400A, C530S350000, C424S093200

Reexamination Certificate

active

07838495

ABSTRACT:
Inhibition of the proliferation of hormone refractory prostate cancer cells is achieved by administering EPB1, an ErbB3 binding protein, in combination with another anti-proliferation therapy such as administration of antiandrogens, other anticancer agents, radiation therapy, or surgery. Administration of EPB1 reverses the phenotype of hormone-resistant prostate cancer cells to hormone-sensitive prostate cancer cells.

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