Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-06-27
2006-06-27
Weber, Jon (Department: 1653)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C512S008000
Reexamination Certificate
active
07067480
ABSTRACT:
This invention relates to the use of a phosphorylcholine-containing glycoprotein in the treatment or prophylaxis of diseases associated with inflammation. In particular, the present invention relates to the use of ES-62 for the treatment or prophylaxis of autoimmune diseases associated with abnormal inflammation, such as rheumatoid arthritis.
REFERENCES:
Laan et al., “Glucocorticosteroids in the management of rheumatoid arthritis”, 1999, Rheumatology (Oxford), 38(1), 6-12.
H.S. Goodridge et al.;Modulation of Macrophage Cytokine Production by ES-62, a Secreted Product of the Filarial Nematode Acanthocheilonema viteae; The Journal of Immunology; 2001; pp. 940-945; vol. 167 (XP-002243871).
W. Harnett et al.;Modulation of the host immune system by phosphorylcholine-containing glycoproteins secreted by parasitic filarial nematodes; Biochimica Et Biophysica Acta; 2001; pp. 7-15; vol. 1539 (XP-002243872).
M. Whelan et al.;A Filarial Nematode-Secreted Product Signals Dendritic Cells to Acquire a Phenotype that Drives Development of Th2 Cells; The Journal of Immunology; 2000; pp. 6453-6460; vol. 164 (XP-002243873).
W. Harnett et al.;Immunomodulation by Filarial Nematode Phosphorylcholine-containing Glycoproteins; Parasitic Nematodes; 2001; pp. 399-414; Cabi Publishing; Wallingford, UK (XP-001152690).
W. Harnett et al.;Immunomodulatory properties of a phosphorylcholine-containing secreted filarial glycoprotein; Parasite Immunology; 1999; pp. 601-608 (XP-002243874).
Copy of International Search Report for PCT/GB02/04310 completed Jun. 11, 2003.
Copy of International Preliminary Examination Report for PCT/GB02/04310 completed Dec. 9, 2003.
Haslam, S., et al., “Characterisation of the Phosphorylcholine-Containing N-Linked Oligosaccharides in the Excretory-Secretory 62 kDa Glycoprotein ofAcanthocheilonema viteae,” Molecular and Biochemical Parasitology, 1997, pp. 53-66, vol. 85, Elsevier Science B.V.
Harnett, W., et al., “Acanthocheilonema viteae: Phosphorylcholine Is Attached to the Major Excretory-Secretory Product via an N-Linked Glycan,”Experimental Parasitology, 1993, pp. 498-502, vol. 77, Academic Press, Inc.
Harnett, W., et al., “Molecular Cloning and Demonstration of an Aminopeptidase Activity in a Filarial Nematode Glycoprotein,”Molecular and Biochemical Parasitology, 1999, pp. 11-23, vol. 104, Elsevier Science B.V.
Houston, K., and Harnett, W., “Prevention of Attachment of Phosphorylcholine to a Major Excretory-Secretory Product ofAcanthocheilonema viteaeUsing Tunicamycin,”American Society of Parasitologists, 1996, pp. 320-324, vol. 82(2).
Leung, B., et al., “Combined Effects of IL-12 and IL-18 on the Induction of Collagen-Induced Arthritis,”The Journal of Immunology, 2000, pp. 6495-6502, The American Association of Immunologists.
Piedrafita, D., et al., “Protective Immune Responses Induced by Vaccination with an Expression Genomic Library ofLeishmania major,” The Journal of Immunology, 1999, pp. 1467-1472, The American Association of Immunologists.
Harnett Margaret M.
Harnett William
McInnes Iain B.
Alston & Bird LLP
Noakes Suzanne M.
The University Court of the University of Glasgow
University of Strathclyde
Weber Jon
LandOfFree
Compositions and methods of use for anti-inflammatory agents does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Compositions and methods of use for anti-inflammatory agents, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods of use for anti-inflammatory agents will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3654770