Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-01-17
2006-01-17
Wilson, James O. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S458000, C549S399000, C549S403000, C424S736000
Reexamination Certificate
active
06987125
ABSTRACT:
Compositions and methods for the treatment, reduction and/or prevention of cardiovascular diseases and disorders are described. Individuals at high risk for developing or having cardiovascular disease or disorder may be treated with an effective dose of a polymethoxyflavone including limocitrin derivatives, quercetin derivatives, naturally occurring polymethoxyflavones, tocotrienols, and mixtures of these compounds.
REFERENCES:
patent: 3867541 (1975-02-01), Robbins
patent: 2001/0055627 (2001-12-01), Guthrie et al.
Phytochemistry , vol. 11, pp. 2283-2288, 1972 (previously submitted by applicant on 1449 mailed May 9, 2000).
Cook et al., Nutritional Biochemistry, vol. 7, pp. 66-76, 1996.
Block, G. et al., “Fruit, Vegetables, and Cancer Prevention: A Review of the Epidemiological Evidence”,Nutrition and Cancer,vol. 18, (1), pp. 1-29, 1992.
Boring, C. et al., “Cancer Statistics, 1993”,A Cancer Journal for Clinicians,vol. 43, pp. 7-27, Jan./Feb. 1993.
Castelli, W., et al., “Incidence of Coronary Heart Disease and Lipoprotein Cholesterol Levels”,JAMA,vol. 256, (20), pp. 2835-2838, Nov. 28, 1986.
Cook, N.C., et al., “Flavonoids-Chemistry, Metabolism, Cardioprotective Effects, and Dietary Sources”,J. Nutr. Biochem.,vol. 7, pp. 66-76, 1996.
Cummings, F., et al., “Adjuvant Tamoxifen Treatment of Elderly Women with Stage II Breast Cancer”,Annals of Internal Medicine,vol. 103, pp. 324-329, 1985.
Dreyer, D.L., et al., “Flavonoids of Citrus-VIII Synthesis of Limocitrol, Limocitrin and Spinacetin”,Tetrahedron,vol. 20, pp. 2977-2983, 1964.
Gryglewski, R., et al., “On the Mechanism of Antithrombotic Action of Flavonoids”,Biochem. Pharmacology,vol. 36, (3), pp. 317-322, 1987.
Hertog, M., et al., “Content of Potentially Anticarcinogenic Flavonoids of 28 Vegetables and 9 Fruits Commonly Consumed in The Netherlands”,J. Agric. Food Chem.,vol. 40, pp. 2379-2383, 1992.
Hertog, M., et al., “Content of Potentially Anticarcinogenic Flavonoids of Tea Infusions, Wines, and Fruit Juices”,J. Agric. Food Chem.,vol. 41, pp. 1242-1246, 1993.
Horowitz, R., et al., “Flavonoids of Citrus. V. Structure of Limocitrin”,J. Org. Chem.,vol. 26, pp. 2899-2902, 1961.
Keli, S., et al., “Dietary Flavonoids, Antioxidant Vitamins, and Incidence of Stroke”,Arch. Inter. Med.,vol. 156, pp. 637-642, Mar. 25, 1996.
Kuhnau, J., “The Flavonoids. A Class of Semi-Essential Food Components: Their Role in Human Nutrition”,World Rev. Nutr. Diet,vol. 24, pp. 117-191, 1976.
Steinmetz, K., et al., “Vegetables, Fruit, and Cancer. I. Epidemiology”,Cancer Causes Control,vol. 2, pp. 325-357,1991.
Sattin, R., et al., “Family History and the Risk of Breast Cancer”,JAMA,vol. 253, (13), pp. 1908-1913, Apr. 5, 1985.
Steinmetz, K., et al., “Vegetables, Fruit, and Cancer. II. Mechanisms”,Cancer Causes Control,vol. 2, pp. 427-442, 1991.
Tatum, J., et al., “Six New Flavonoids FromCitrus”, Phytochemistry,vol. 11, pp. 2283-2288, 1972.
Guthrie Najla
Horowitz Sylvia
Kurowska Elzbieta Maria
Manthey John A.
Fado John D.
Owens Howard V.
Poulos Gail E.
The United States of America as represented by the Secretary of
Wilson James O.
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