Compositions and methods of treating psoriasis with vinyligs of

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424344, A61K 3107

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039669670

ABSTRACT:
The C20 and C22 vinylogs of desmethyl retinoic acid have been found highly effective in promoting wound healing, in the treatment of acne, psoriasis and related skin disorders. The acid is applied to the site as a solution, ointment or powder. These acids are the most effective yet found for such purposes yet do not have some of the undesirable side effects of retinoic acid.

REFERENCES:
patent: 3689667 (1972-09-01), Lee
Frost et al., Jama. 207, No. 10, (3/10/69) pp. 1863-1868.
Fry et al., British J. of Dermatology, vol. 83, (1970), pp. 391-396.
Fredriksson, Dermatologica 142, (1971), pp. 133-136.
Orfands, et al., British J. of Dermatology (1973), pp. 167-182.

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