Compositions and methods of making and using human full length T

Details Compositions and methods of making and using human full length T Compositions and methods of making and using human full length T

1994-07-07

1997-02-11

Jones, W. Gary

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Binds expression product or fragment thereof of...

435 6, 435 912, 536 231, 536 243, A61K 39395, C12Q 168, C12P 1934, C07H 2102

Patent

active

056018207

ABSTRACT:
The amino acid sequence of the full length version of the human neurotrophic factor receptor TRK B and a nucleotide sequence encoding it are disclosed. Transformed host cells and transgenic animals containing nucleic acid molecules encoding full length human TRK-B are disclosed. Probes, primers and antisense molecules identical and complementary to the nucleotide sequence that encodes full length human TRK-B, particularly the intracellular portion of the receptor are disclosed. Monoclonal antibodies that bind to the full length human TRK-B protein are disclosed. Methods of using and kits which include probes, primers, antisense molecules and monoclonal antibodies are disclosed.

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