Compositions and methods of effecting contraception utilizing me

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514415, 514419, A61K 3156, A61K 3140, A61K 31405

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active

048553050

ABSTRACT:
A method of effecting contraception in human females comprises administering an ovulation-inhibiting amount of melatonin. Optionally, the melatonin is administered in combination with a progestogen and/or an estrogen. The administration of melatonin also provides a method of preventing breast cancer in women.

REFERENCES:
patent: 4087444 (1978-05-01), Flaugh et al.
patent: 4390531 (1983-06-01), Edgren
patent: 4425339 (1984-01-01), Pitchford
patent: 4614807 (1986-09-01), Flaugh
Nordlund et al., J. Clin. Endocrin. Metab. 45: 768-770 (1977).
Weinberg et al., J. Clin. Endocrin. Metab. 51: 161-162 (1980).
Wright et al., Clinical Endocrinology 24: 375-382 (1986).
Cardinelli, Endocrine Reviews 2: 237-346 (1981).
Reiter, J. Obstet and Gynaecol. 6 (Supp. 2): 577-581 (1986).
William, Br. Vet. J. 140(4): 407-8 (1984).
Arendt et al., J. Endocrinol. 97:395-400 (1983).
Kennaway et al., Endocrinology 110(5): 1766-72 (1982).
Reiter, in Slott et al., Ed. Brain Endocrine Interaction III. Neural Hormones and Reproduction, Basel Karger (1978).
Berga, et al., J. Clin. Endocrinol. Metabl., 242-244 (1988).
Webley, et al., J. Clin. Endocrinol. Metab. 63:323-328 (1986).
Carr, et al., J. Clin. Endocrinol. Metab. 53: 224-225 (1981).
Tamarkin, et al., Endocrinology 99: 1534-1541 (1976).
Bittman, Science 1978 202 (4368) 648-50 (1978).
Guidelines for the Toxicological and Clinical Assessment and Post Registration Surveillance of Sterional Contraceptive Drugs by the World Health Organization (1987).
Kirton, in Animal Models for Predicting Toxicity of Fertility Control Agents, Raven Press, Serjo et al. ED. 455-460 (1980).
Kirton, in Animal Models for Predicting Toxicity of Fertility Control Agents, Raven Press, Serjo et al. ED. 455-460 (1980).
Bosu et al., Contraception 13: 677-684 (1976).
Perlow et al., Brain Res., 182:211-216 (1980).
Fideleff et al., J. Clin. Endocrin. Metab., 42(6): 1014 (1976).
Brzezinski et al., J. Clin. Endocrin. Metab. 66:(5):891 (1987).
Reiter et al., J. Neural Trans. Supp. 13:209 (1978).
Walker et al., Endocrinology 114($):1074 (1984).
Kumar et al., "Nasal Sprays for Controlling Ovulation in Rehsus Monkeys".
Kumar et al., Nature 270:532 (1977).
Reiter, Journal of Obstetrics and Gynecology (1986), S77-81.
Kumar, et al. Satellite Symp. 7th Congr. Int. Primatol Soc. Bangalore 1979, pp. 169-175.
Ying et al., Endocrinology 92:333, 1973.
Flaugh, et al., Journal of Medicinal Chem, 1979, vol. 22, No. 1.
Chu et al., Endocrinology, 75: 238, 1964.
Tamarkin, et al., Science, vol. 227, Jan. 1985, 714-720.
Espey, et al., Fertil Steril 38 (2) 1982, 238-247.
Sharpe et al., Theriogenology 26(5), 1986, 621-630.
Nowak et al., J. Reprod Fertil 74(1), 1985, 287-294.
Kennaway, et al., J. Reprod Fertil 70(1), 1984, 39-46.
Chemineau, et al., J. Reprod. Fertil 78(2), 1986, 497-504.
Nett et al., Theriogenology 17(6), 1982, 645-654.
Fiske et al., Endocrinology, vol. 114, No. 2, 1984, pp. 407-410.
Webley et al., J. Reprod. Fert. (1986) 78, 711-717.
Webley et al., J. Clin. Endocrinol. Metab., 63(2), 323-8.
Tamarkin, Science, vol. 26, 28 May 1982, 1003-1005.
Tamarkin et al., Cancer Research, vol. 41 4432-4436, (1981), 4432-4435.
Danforth et al., J. Clin. Oncol 3 (7), 1985, 941-948.
Heywood, in Animal Models in Human Reproduction, Raven Press, M. Serjo et al., Ed. 433-442 (1980).

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