Compositions and methods improving renal function

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S093440

Reexamination Certificate

active

07998470

ABSTRACT:
Compositions and methods for improving renal function withStreptococcusprobiotic bacteria selected for converting nitrogenous waste into non-toxic compounds in vivo are provided. By reducing the levels of nitrogenous wastes, the instant compositions reduce kidney burden.

REFERENCES:
patent: 4022883 (1977-05-01), Setala
patent: 4218541 (1980-08-01), Ackerman
patent: 4427701 (1984-01-01), Morley
patent: 4970153 (1990-11-01), Kobashi et al.
patent: 5032399 (1991-07-01), Gorbach et al.
patent: 5116737 (1992-05-01), McCoy
patent: 5145697 (1992-09-01), Cajigas
patent: 5358729 (1994-10-01), Ohkuma et al.
patent: 5531988 (1996-07-01), Paul
patent: 5716615 (1998-02-01), Cavaliere Vesely et al.
patent: 5733568 (1998-03-01), Ford
patent: 5840318 (1998-11-01), Marshall et al.
patent: 6008027 (1999-12-01), Langner
patent: 6080401 (2000-06-01), Reddy et al.
patent: 2002/0192202 (2002-12-01), Naidu
patent: 2003/0147995 (2003-08-01), Koss et al.
patent: WO 99/49877 (1999-10-01), None
patent: WO 00/71138 (2000-11-01), None
patent: WO 00/71139 (2000-11-01), None
Shimizu et al., “Chemisorbent for medical use. Dialdehydestarc=h-urease conjugate for removal of area as ammonia”, Chemical Abstracts 1955 103:129004d.
Asher et al., “Projections and measurements of in vivo performance of liquid membrane capsules”,Kidney Int. 1976 10:S-254-S-258.
Bezkorovainy A., “Probiotics:determinants of survival and growth in the gut1-3”,Am. J. Clin. Nutr. 2001 73(Suppl): 399S-405S.
Bliss et al., “Supplementation with gum arabic fiber increases fecal nitrogen excretion and lowers serum urea nitrogen concentration in chronic renal failure patients consuming a low-protein diet1-4”,Am. J. Clin. Nutr. 1996 63:392-398.
Chang, T.M.S. (Artificial Cells, Chapter 5, in Biomedical Applications of Microencapsulation, edited by Lim, F. CRC Press Florida, pp. 86-100.
Chang T.M.S., “Assessments of clinical trials of charcoal hemoperfusion in uremic patients”,Clin. Neph. 1979 11:111-119.
Clark et al., Perfusion of Isolated Intestinal Loops in the Management of Chronic Renal Failure,Trans. Am. Soc. Artif. Intrn. Organs1962 8:246-251.
Cummings J.H. et al., Prebiotic digestion and fermentation1-3,Am. J. Clin. Nutr. 2001 73(Suppl) : 415S-420S.
Dunn et al., “Gas Chromatographic Determination of Free Mono-, Di-, and Trimethylamines in Biological Fluids”,Analytical Chemistry1976 48:41-44.
Einbacher and Carter, “The Role of the Microbial Flora in uremia”,J. Exp. Med. 1966 123:239-250.
Okada, K. and Takahashi, S., “Correction by oral adsorbent of abnormal digestive tract milieu in rats with chronic renal failure”,Nephrol. Dial. Transplant. 1995 10:671-676.
Owadu, A. and Shiigai, T., “Effects of Oral Adsorbent AST-120 Concurrent with a Low-Protein Diet on the Progression of Chronic Renal Failure”,Am. J. Nephrol. 1996 16:124-127.
Prakash, S. and Chang, T.M.S., “Microencapsulated genetically engineered liveE. coliDH5 cells administered orally to maintain normal plasma urea level in uremic rats”,Nature Med. 1996 2:883-887.
Prakash S. and Chang T.M.S., “Preparation and in Vitro Analysis of Microencapsulated Genetically EngineeredE. coliDH5 Cells for Urea and Ammonia Removal”, Biotechnology and Bioengineering 1995 46:621-26.
Setala, K., “Bacterial enzymes in uremia management”,Kidney Intl. 1978 8:S-194-S-202.
Shimizu et al., “Removal of uremic waste metabolites (chiefly urea) by chemically surface-treated dialdehyde starch”,Chemical Abstracts1982 97:222900 3p.
Sparks R.E., “Gastrosorbents in the therapy of uremia: Inferences from intestinal loop dialysis”,Kidney Int.1975 Suppl 7:S-373-S-376.
Twiss E.E. and Kolff W.J., “Treatment of Uremia by Perfusion of an Isolated Intestinal Loop”,JAMA1951 146:1019-1022.
Yatzidis et al., “Newer oral sorbents in uremia”,Clinical Nephrology1979 11:105-106.
Waynforth, H.B. and Flecknell, P.A. Nephrectomy. In: Experimental and surgical techniques in the rat. 2nd ed., 1992, Academic Press (Harcourt, Brace, Jovanovich), London, pp. 29, 274-275.
Wrong O., “Various views on anonymity”,Nature Medicine1997 2-3.
Holzapfel et al., “Overview of gut flora and probiotics”, International Journal of Food Microbiology 1998 41:85-101.
Marteau et al., “Protection from gastrointestinal diseases with the use of probiotics1-3”, Am J. Clin Nutr 2001 73:430S-436S.
Orrhage and Nord, “Bifidobacteria and Lactobacilli in Human Health”, Drugs Exptl. Clin. Res. 2000 XXVI(3):95-111.
Pateras et al., “The Role of Intestinal Perfusion in the Management of Chronic Uremia”, Trans. Amer. Soc. Artif. Int. Organs 1964 X:292-295.
von Wright and Salminen, “Probiotics:established effects and open questions”, Eur J Gastroenterol Hepatol 1999 11(11):1195-1198.
Bliss et al., “Supplementation with gum arabic fiber increases fecal nitrogen excretion and lowers serum urea nitrogen concentration in chronic renal failure patients consuming a low-protein diet1-4”,Am. J. Clin. Nutr. 1996 63:392-398.
Chang, T.M.S., “Artificial Cells”, Chapter 5, inBiomedical Applications of Microencapsulation, edited by Lim, F. CRC Press Florida, pp. 86-100.
Clark et al., “Perfusion of Isolated Intestinal Loops in the Management of Chronic Renal Failure”,Trans. Am. Soc. Artif. Intrn. Organs1962 8:246-251.
Dunn et al., “Gas Chromatographic Determination of Free Mono-, Di-, and Trimethylamines in Biological Fluids”,Analytical Chemistry1976 48:41-44.
Einbacher and Carter, “The Role of the Microbial Flora in uremia”,J. Exp. Med. 1966 123:239-250.
Friedman et al., “Hypertrigylceridemia Responsive to Charcoal Sorption”,Proc. Clin. Dia. Trans. Forum1977 7:183-184.
Goldenhersh et al., “Effect of microencapsulation on competitive adsorption in intestinal fluids”,Kidney Int. 1976 10:S251-S253.
Gotch et al., “Theoretical Considerations on Molecular Transport in Dialysis and Sorbent Therapy for Uremia”,Journal of Dialysis1976-1977 1(2):105-144.
Kjellstrand et al., “On the Clinical use of Microencapsulated Zirconium Phosphate-Urease for the Treatment of Chronic Uremia”,Trans. Am. Soc. Artif. Intern. Organs1981 27:24-29.
Kolff, W.J., “Longitudinal perspectives on sorbents in uremia”,Kidney Int.1976 10:S211-S214.
Nagano et al., “Pharmacological properties of chitosan-coated dialdehyde cellulose (chitosan DAC), a newly developed oral adsorbent (II). Effect of chitosan DAC on rats with chronic renal failure induced by adriamycin”, Medline Abstract UI 96058336 1995.
Niwa et al., “Indoxyl Sulfate and Progression of Renal Failure: Effects of a Low-Protein Diet and Oral Sorbent on Indoxyl Sulfate Production in Uremic Rats and undialyzed Uremic Patients”,Miner. Electr. Metab. 1997 23:179-184.
Okada, K. and Takahashi, S., “Correction by oral adsorbent of abnormal digestive tract milieu in rats with chronic renal failure”,Nephrol. Dial. Transplant. 1995 10(5):671-676.
Owadu, A. and Shiigai, T., “Effects of Oral Adsorbent AST-120 Concurrent with a Low-Protein Diet on the Progression of Chronic Renal Failure”,Am. J. Nephrol. 1996 16(2):124-127.
Prakash, S. and Chang, T.M.S., “Microencapsulated genetically engineered liveE. coliDH5 cells administered orally to maintain normal plasma urea level in uremic rats”,Nature Med. 1996 2:883-887.
Prakash, S. and Chang, T.M.S., “Preparation and in Vitro Anaylsis of Microencapsulated Genetically EngineeredE. coliDH5 Cells for Urea and Ammonia Removal”,Biotechnology and Bioengineering1995 46:621-626.
Setala, K., “Bacterial enzymes in uremia management”,Kidney Intl Suppl. 1978 8:S194-202.
Shimizu et al., “Removal of uremic waster metabolites (chiefly urea) by chemically surface-treated dialdehyde starch”,Chemical Abstra

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compositions and methods improving renal function does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compositions and methods improving renal function, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compositions and methods improving renal function will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2619829

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.