Compositions and methods for vaccinating against HSV-2

Details Compositions and methods for vaccinating against HSV-2 Compositions and methods for vaccinating against HSV-2

2007-07-20

2009-12-08

Salimi, Ali R. (Department: 1648)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

C435S006120

Reexamination Certificate

active

07628993

ABSTRACT:
This invention relates to a method for systemic immune activation which is effective for eliciting both a systemic, non-antigen specific immune response and a strong antigen-specific immune response in a mammal. The method is particularly effective for protecting a mammal from herpes simplex virus. Also disclosed are therapeutic compositions useful in such a method.

REFERENCES:
patent: 5654174 (1997-08-01), Cohen et al.
patent: 6375952 (2002-04-01), Koelle et al.
patent: 6413518 (2002-07-01), Koelle et al.
patent: 6814969 (2004-11-01), Koelle et al.
patent: 6855317 (2005-02-01), Koelle et al.
patent: 7037509 (2006-05-01), Koelle et al.
patent: 7078041 (2006-07-01), Koelle et al.
patent: 2005/0163794 (2005-07-01), Koelle et al.
patent: 2006/0216304 (2006-09-01), Koelle et al.
patent: WO00/57917 (2000-10-01), None
patent: WO01/32221 (2001-05-01), None
patent: WO03/104400 (2003-12-01), None
Nakamura et al, Nucleic Acid Research, 2000, 28: 292.
Dong, L, et al. “Cellular and humoral immune responses to HSV-2 tegument proteins in H-2D mice after DNA vaccination”,31st International Herpesvirus Workshop, Seattle, WA, Jul. 22-27, 2006, Abstract 9.16.
Ferrari, Marilyn E., et al. “Synergy between cationic lipid and co-lipid determines the macroscopic structure and transfection activity of lipoplexes”,Nucleic Acids Research(2002) 30(8):1808-1816.
Muller, W., et al. “Cellular and humoral immune responses induced by Plasmid DNA vaccines encoding HSV-2 Tegument Proteins”,44th Annual Meeting of the Infectious Diseases Society of America(IDSA), Toronto, Canada, Oct. 12-15, 2006, Abstract 615, p. 166.
Muller, W.J., et al. “HSV-2 tegument directed T-cells develop after vaginal infection in Balb/c mice and tegument-based vaccines partially protect against lethal challenge”,32nd International Herpesvirus Workshop, Asheville, NC, Jul. 2007, Abstract 10.20.
Koelle, D.M., et al. “Immunogenicity and protective efficacy of plasmid DNA vaccines encoding HSV-2 tegument proteins in a murine intravaginal challenge model”,17th International Society of Sexually Transmitted Diseases Research(ISSTDR), Seattle, WA, Jul. 2007, Abstract 317.

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