Compositions and methods for using low-swell clays in nicotine c

Details Compositions and methods for using low-swell clays in nicotine c Compositions and methods for using low-swell clays in nicotine c

1996-05-17

1998-03-10

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424487, A61L 1520, A61L 1526

Patent

active

057258767

ABSTRACT:
A dermal composition for transdermal administration of nicotine includes a blend of: one or more acrylic-based polymers in an amount of from about 10-90% w/w, nicotine in an amount of from about 3 to 15% w/w, and a cohesiveness increasing amount of one or more low-swell clays in an amount of from about 0.5 to 30% w/w. The low-swell clay has a swell of 3-23 mls as determined by the bentonite USP/NF swelling power test. Also disclosed is a method for producing a dermal composition and a method for increasing the cohesiveness of a nicotine containing dermal composition.

REFERENCES:
patent: 5077104 (1991-12-01), Hunt et al.
patent: 5300291 (1994-04-01), Sablotsky et al.
patent: 5474783 (1995-12-01), Mikanda et al.

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