Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-10-18
2005-10-18
Jones, Dwayne (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S415000, C514S443000, C514S733000, C514S731000, C424S600000, C424S601000, C424S602000, C424S603000, C424S604000, C424S605000
Reexamination Certificate
active
06956054
ABSTRACT:
Treatment of warm-blooded animals having a tumor or non-malignant hypervascularation, by administering a sufficient amount of a cytotoxic agent formulated into a phosphate prodrug form having substrate specificity for microvessel phosphatases, so that microvessels are destroyed preferentially over other normal tissues, because the less cytotoxic prodrug form is converted to the highly cytotoxic dephosphorylated form.
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patent: 6538038 (2003-03-01), Pero et al.
Stein, J. H., Editor-in-Chief, Internal Medicine, Fourth Edition, Chapters 71 and 72, 1994.
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Chen Zhi
Mocharla Vani P.
Pero Ronald W.
Pinney Kevin G.
Sherris David
Baylor University
Biswas Naomi S.
Elrifi Ivor R.
Jones Dwayne
Mintz Levin Cohn Ferris Glovsky and Popeo P.C.
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