Compositions and methods for treatment of microbial infections

Details Compositions and methods for treatment of microbial infections Compositions and methods for treatment of microbial infections

2005-08-16

2005-08-16

Graser, Jennifer E. (Department: 1645)

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

C424S234100, C424S197110, C435S243000, C435S252300, C435S320100

Reexamination Certificate

active

06929798

ABSTRACT:
The present invention relates to methods and compositions for treatment of microbial infections and for the enhancement of resistance to infection. The invention comprises administration of an effective amount of bacterial lysate compositions for the treatment of pathological conditions of microbial infections. The present invention can also be used to enhance the immune system to prevent infections by the administration of an effective amount of the compositions.

REFERENCES:
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patent: 6294177 (2001-09-01), Fattom
Ruah et al., Efficacy of a Polyvalent Bacterial Lysate in Children with Recurrent Respiratory Tract Infections, Advances in Therapy. Jul./Aug. 2001, pp. 151-162, vol. 18, No. 4.
Ruedl et al., Immune Response in the Lungs Following Oral Immunization with Bacterial Lysates of Respiratory Pathogens, Clinical and Diagnostic Laboratory Immunology, Mar. 1994, pp. 150-154, vol. 1, No. 2.
West et al., Respiratory Infections with Pseudomonas aeruginosa in Children with Cystic Fibrosis, JAMA, Jun. 12, 2002, pp. 2958-2967, vol. 287, No. 22.
Rossi et al., Naturally Occuring Immune Response Against Bacteria Commonly Involved in Upper Respiratory Tract Infections: Analysis of the Antigenspecific Salivary IgA Levels, Immunology Letters, 2003, pp. 85-91, vol. 86.
Puigdollers et al., Immunoglobulin Production in Man Stimulated by an Orally Adminstered Bacterial Lysate, Respiration, 1980, pp. 142-149, vol. 40.
Kosorok et al., Acceleration of Lung Disease in Children with Cystic Fibrosis AfterPseudomonas aeruginosaAcquisition, Pediatric Pulmonology, 2001, pp. 277-287, vol. 32.

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