Compositions and methods for treatment and detection of...

Details Compositions and methods for treatment and detection of... Compositions and methods for treatment and detection of...

2007-04-17

2007-04-17

Siew, Jeffrey (Department: 1642)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

C424S155100, C424S185100, C514S04400A, C536S023100, C536S024300

Reexamination Certificate

active

10188840

ABSTRACT:
The invention provides a method for inhibiting proliferation of cancer cells, as well as methods for detecting and treating various cancers, including cancer of the brain, lung, breast, prostate and colon. The method comprises contacting a cancer cell with a molecule that disrupts the biological activity of a GDOX molecule. In one embodiment, the molecule is an antibody directed against a GDOX peptide. In other embodiments, the molecule is an antisense nucleotide directed against a GDOX nucleic acid molecule, or a vaccine comprising a GDOX peptide or a polynucleotide encoding a GDOX peptide. The invention additionally provides methods for detecting and treating cancer using GDOX-related molecules.

REFERENCES:
patent: 5840708 (1998-11-01), Weiss
patent: 5912143 (1999-06-01), Bandman et al.
patent: 2002/0147147 (2002-10-01), Molling et al.
patent: 1 074 617 (2001-02-01), None
patent: WO 02/22660 (2002-03-01), None
patent: WO 200222660 (2002-03-01), None
Sherman , M.I. Annals of NY Acad. Sci. , 1990,616:201-204.
Holt ,J.Mol Med Today , 1996, 2:184-185.
Rojanasakul ,Y. Advanced Drug Delivery Reviews , 1996,18:115-131.
Branch ,A.D.Tibs, Feb. 1998 , 23: pp. 45-50.
Hanash , S. Nature Reviews, Applied Proteomics, Mar. 2005, 9-14.
Freshney , I., Culture of Animal Cells, A Manual of Basic Technique, Alan R. Liss, Inc., 1983, New York, p. 4.
Hartwell et al .,Science, 1997, 278:64-1068).
Dermer, G., Bio/Technology, 1994, 12:320.
Gura , T., Science, 1997, 278:1041-1042.
Jain , R, K., Sci. Am., 1994, 271:58-65.
Curti ,B.D.,Crit. Rev. in Oncology/Hematology, 1993, 14:29-39.
Bowie et al (Science, 1990, 257:1306-1310).
Burgess et al ( J of Cell Bio. 111:2129-2138, 1990).
Lazar et al (Molecular and Cellular Biology, 1988, 8:1247-1252).
Sambrook et al, eds, 1989, 2nd ed, Molecular Cloning, a laboratory manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, p. 11.52.
Wang et al (PNAS, 1995, 92:3318-3322).
Miller (1995, FASEB J., vol. 9, pp. 190-199).
Deonarain (1998, Expert Opin. Ther. Pat., vol. 8, pp. 53-69).
Verma (Sep. 1997, Nature, vol. 389, pp. 239-242).
Crystal (1995, Science, vol. 270, p. 404-410).
Montesano, R et al,1996, Intl J Cancer, 69(3): 225-235.
Burmer, GC et al, 1991, Environmental Health perspectives, 93: 27-31.
Busken, C et al, Digestive Disease Week Abstracts and Itinerary Planner, 2003, abstract No. 850.
W.K. Cavenee, “Accumulation of Genetic Defects during Astrocytoma Progression,” Cancer, 1992, 70(6): 1788-1793.
L.M. Liau et al., “Identification of a Human Glioma-associated Growth Factor Gene,granulin, Using Differential Immuno-absorption,” Cancer Research, 2000, 60: 1353-1360.
L.M. Liau et al., “Microarrays and the Genetic Analysis of Brain Tumors,” Current Genomics, 2002, 3(1): 33-41.
M. Nagane et al., “Advances in the Molecular Genetics of Gliomas,” Current Opinion in Oncology, 1997, 9: 215-222.
L. Zhang et al., “Gene Expression Profiles in Normal and Cancer Cells,” Science, 1997, 276: 1268-1272.
T.M. Strom et al., NCBI Accession No. AJ005896, 1998, 2pp.
A Schmitt et al., NCBI Accession No. AX011651, 2000, 1pp.
R. Strausberg, NCBI Accession No. BC021213, 2002, 2pp.
T. Isogai et al., NCBI Accession No. AK023433, 2002, 2pp.
W.B. Li et al., dbEST Id 7913479, NCBI Accession No. AL578513, 2001, 2pp.
W.B. Li et al., dbEST Id 7891055, NCBI Accession No. AL556099, 2001, 2pp.
W.B. Li et al., dbEST Id 7897665, NCBI Accession No. AL562709, 2001, 2pp.
K. Blechschmidt et al., NCBI Accession No. AF196779, 1999, 61pp.
R. Strausberg, dbEST Id 11609265, NCBI Accession No. BM925837, 2002, 2pp.
W.B. Li et al., dbEST Id 7890454, NCBI Accession No. AL555498, 2001, 2pp.
R. Strausberg, dbEST Id 9642741, NCBI Accession No. BI823463, 2001, 2pp.
R. Strausberg, dbEST Id 11116863, NCBI Accession No. BM544778, 2002, 2pp.
R. Strausberg, dbEST Id 8568806, NCBI Accession No. BG828872, 2001, 2pp.
R. Strausberg, dbEST Id 11137339, NCBI Accession No. BM563934, 2002, 2pp.
R. Strausberg, dbEST Id 11120666, NCBI Accession No. BM548567, 2002, 2pp.
R. Strausberg, dbEST Id 6786993, NCBI Accession No. BF339883, 2000, 2pp.
R. Strausberg, dbEST Id 11124903, NCBI Accession No. BM 552522, 2002, 2pp.
R. Strausberg, dbEST Id 11363630, NCBI Accession No. BM801598, 2002, 2pp.
R. Strausberg, dbEST Id 7417187, NCBI Accession No. BF967572, 2001, 2pp.
W.B. Li et al., dbEST Id 7912948, NCBI Accession No. AL577982, 2001, 2pp.
R. Strausberg, dbEST Id 6961642, NCBI Accession No. BF525597, 2000, 2pp.
R. Strausberg, dbEST Id 9823795, NCBI Accession No. BI914036, 2001, 2pp.
R. Strausberg, dbEST Id 8519963, NCBI Accession No. BG759829, 2001, 2pp.
R. Strausberg, dbEST Id 9641131, NCBI Accession No. BI821858, 2001, 2pp.
R. Strausberg, dbEST Id 7128546, NCBI Accession No. BF663215, 2000, 2pp.
R. Strausberg, dbEST Id 9817876, NCBI Accession No. BI908155, 2001, 2pp.
R. Strausberg, dbEST Id 6682186, NCBI Accession No. BF237784, 2000, 2pp.
R. Strausberg, dbEST Id 9643781, NCBI Accession No. BI824500, 2001, 2pp.
R. Strausberg, dbEST Id 7418555, NCBI Accession No. BF968709, 2001, 2pp.
R. Strausberg, dbEST Id 9826444, NCBI Accession No. BI916663, 2001, 2pp.
R. Strausberg, dbEST Id 7537145, NCBI Accession No. BF 980663, 2001, 2pp.
T. Ota et al., dbEST Id 6563809, NCBI Accession No. AU134850, 2000, 2pp.
R. Strausberg, dbEST Id 9824007, NCBI Accession No. BI914246, 2001, 2pp.
R. Strausberg, dbEST Id 6038328, NCBI Accession No. BE784473, 2000, 2pp.
R. Strausberg, dbEST Id 9608861, NCBI Accession No. BI767996, 2001, 2pp.
R. Strausberg, dbEST Id 9414614, NCBI Accession No. BI600570, 2001, 2pp.
R. Strausberg, dbEST Id 8963557, NCBI Accession no. BI199514, 2001, 2pp.
R. Strausberg, dbEST Id 5033672, NCBI Accession No. BE263463, 2000, 2pp.
R. Strausberg, dbEST Id 5686922, NCBI Accession No. BE514230, 2000, 2pp.
M.F. Bonaldo et al., dbEST Id 11633144, NCBI Accession No. BM931103, 2002, 2pp.
M.F. Bonaldo et al., dbEST Id 11301541, NCBI Accession No. BM720608, 2002, 2pp.
R. Strausberg, dbEST Id 8480717, NCBI Accession No. BG720198, 2001, 2pp.
R. Strausberg, dbEST Id 7417116, NCBI Accession No. BF967514, 2001, 2pp.
R. Strausberg, dbEST Id 5020715, NCBI Accession No. BE254555, 2000, 2pp.
Database Genbank, Accession No. ABB97608, Tang et al. Gene Sequence, Mar. 21, 2002. SEQ ID No. 876. MPSRCH search report, 2004, pct-us03-21013-2.rag, p. 2

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