Compositions and methods for treating sickle cell disease

Details Compositions and methods for treating sickle cell disease Compositions and methods for treating sickle cell disease

1999-01-19

2000-04-18

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4353201, 435325, 536 231, 530385, C12P 2106, C07H 1700, C07K 14805

Patent

active

060514027

ABSTRACT:
Gene therapy methods and compositions for high level expression of anti-sickling globin proteins in erythroid cells for treating Sickle Cell disease are described.

REFERENCES:
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patent: 5861488 (1999-01-01), Leboulch et al.
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Takekoshi, Ken J., et al., "Retroviral Transfer of a Human .beta.-globin/.delta.-globin Hybrid Gene Linked to .beta. Locus Control Region Hypersensitive Site 2 Aimed at the Gene Therapy of Sickle Cell Disease", Proc. Natl. Acad. Sci., USA, vol. 92, No. 7, pp. 3014-3018 (Mar. 1995).

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