Compositions and methods for treating or preventing...

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

Reexamination Certificate

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Details

C424S185100, C424S190100, C424S193100, C424S197110, C424S234100

Reexamination Certificate

active

10702305

ABSTRACT:
The invention provides polypeptides, polysaccharide-polypeptide conjugates, and expression vectors for treating or preventing pneumococcal infection. The compositions induce an anti-pneumococcal immune response when administered to a mammal. The compositions can be used prophylactically to vaccinate an individual and/or therapeutically to induce a therapeutic immune response in an infected individual.

REFERENCES:
patent: 6342224 (2002-01-01), Bruck et al.
patent: WO 90/06951 (1990-06-01), None
patent: WO 99/03884 (1999-01-01), None
McDaniel, et al., “Immunization with a Plasmid Expressing Pneumococcal Surface protein A (PspA) can Elicit Protection Against Fatal Infection withStreptococcus pneumoniae, ” Gene Therapy, 1997, vol. 4, No. 4, pp. 375-377, see Abstract.

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