Compositions and methods for treating ophthalmic disorders

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C424S093200, C424S093210

Reexamination Certificate

active

07943590

ABSTRACT:
The present invention relates to compositions and methods for treating and/or preventing ocular disorders, diseases or conditions and compositions and methods for treating or preventing ophthalmic conditions and disorders in a subject in need thereof.

REFERENCES:
patent: WO 00/41712 (2000-07-01), None
Iwaguro (Circulation, 2002, vol. 105, p. 732-738).
Chen et al., “Combination of VEGF165/Angiopoietin-1 gene and endothelial progenitor cells for therapeutic neovascularization”Eur. J. Pharmacol., 568:222-230 92007).
Gluzman et al., “Endothelial cells are activated by angiopoeitin-1 gene transfer and produce coordinated sprouting in vitro and arteriogenesis in vivo”,Biochem. Biophys, Res. Comm., 359:263-268 (2007).
Joussen et al., “Suppression of Diabetic Retinopathy with Angiopoietin-1”,Am. J. Pathol., 160(5):1683-1693 (2002).
Nambu et al., “Angiopoietin 1 Prevents Retinal Detachment in an Aggressive Model of Proliferative Retinopathy, but has no Effect on Established Neovascularization”,J. Cell. Physiol., 204:227-235 (2005).

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